The 2025 NFL season officially came to a close when the Seattle Seahawks defeated the New England Patriots in Super Bowl LX at Levi’s Stadium. Now attention shifts to 2026, and the San Francisco 49ers are aiming to retool their roster this offseason and position themselves for another playoff run.

DraftKings Sportsbook has released its early odds for Super Bowl LXI, which will be played at SoFi Stadium on February 14, 2027. The defending champion Seahawks are among the early favorites, tied with the Los Angeles Rams at +950.

49ers’ Super Bowl LXI odds

The 49ers currently hold the 10th-best odds to win Super Bowl LXI at +1700.

Despite finishing 12-5 last season, San Francisco placed third in the NFC West behind the Seahawks and Rams. The 49ers entered Week 18 with a chance to win the division and secure home-field advantage, but fell to Seattle in a pivotal matchup.

Below are the full Super Bowl LXI odds from DraftKings Sportsbook:

Seattle Seahawks: +950
Los Angeles Rams: +950
Buffalo Bills: +1100
Philadelphia Eagles: +1300
New England Patriots: +1300
Baltimore Ravens: +1300
Green Bay Packers: +1400
Detroit Lions: +1400
Los Angeles Chargers: +1500
Kansas City Chiefs: +1500
San Francisco 49ers: +1700
Houston Texans: +1900
Denver Broncos: +1900
Jacksonville Jaguars: +2000
Chicago Bears: +2500
Cincinnati Bengals: +2800
Dallas Cowboys: +3500
Tampa Bay Buccaneers: +4000
Washington Commanders: +6000
Pittsburgh Steelers: +6000
Minnesota Vikings: +6000
Indianapolis Colts: +6000
New York Giants: +7000
Atlanta Falcons: +8000
Tennessee Titans: +10000
New Orleans Saints: +10000
Carolina Panthers: +10000
Cleveland Browns: +15000
New York Jets: +20000
Las Vegas Raiders: +20000
Miami Dolphins: +25000
Arizona Cardinals: +25000

Key factors impacting the 49ers’ 2026 outlook

Injuries played a major role in San Francisco’s 2025 campaign. The absences of cornerstone defenders such as linebacker Fred Warner and defensive end Nick Bosa were significant, as the 49ers finished with just 20 sacks—the fewest total in the NFL.

The hope is that improved health in 2026 could dramatically elevate the team.

Offensively, quarterback Brock Purdy finished the season strong after returning from a turf toe injury. Purdy won six of his final seven regular-season starts, with his only loss coming in the Week 18 showdown against the Seahawks. That reliability at quarterback will bode well for the 49ers in the future.

Financial flexibility will also be a key factor in the 49ers’ offseason approach. According to OverTheCap.com, San Francisco is projected to have approximately $38.6 million in effective cap space, based on an estimated $303.5 million salary cap. However, final cap figures have not yet been announced.

A strong offseason and better injury luck could help the 49ers keep pace—and possibly overtake—the Seahawks and Rams in the NFC West, potentially making their +1700 Super Bowl LXI odds a strong value.