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Best fantasy performances in Indianapolis Colts history
Every season in the NFL produces performances that feel less like a single game and more like statistical outliers — explosive outings where quarterbacks pile up passing yards, running backs break off long scoring runs, and receivers turn routine targets into multi-touchdown afternoons. These are the kinds of games that separate good fantasy weeks from historic ones.
Stacker compiled a ranking of the best fantasy performances in Indianapolis Colts history using data from Stathead. The list includes the highest single-game fantasy scores by quarterbacks, running backs, and wide receivers/tight ends across the franchise’s history, based on standard fantasy scoring.
Best Quarterback fantasy games
#5. Andrew Luck, September 11, 2016
– Stats: 385 Passing Yards, 4 Passing TDs, 0 Interceptions, 21 Rushing Yards
– Game: IND vs DET, 35-39 Loss
#4. Andrew Luck, September 30, 2018
– Stats: 464 Passing Yards, 4 Passing TDs, 0 Interceptions, 11 Rushing Yards
– Game: IND vs HOU, 34-37 (OT) Loss
#3. Peyton Manning, September 28, 2003
– Stats: 314 Passing Yards, 6 Passing TDs, 0 Interceptions
– Game: IND vs NOR, 55-21 Win
#2. Peyton Manning, October 31, 2004
– Stats: 472 Passing Yards, 5 Passing TDs, 1 Interceptions
– Game: IND vs KAN, 35-45 Loss
#1. Peyton Manning, September 23, 2001
– Stats: 421 Passing Yards, 4 Passing TDs, 2 Interceptions, 26 Rushing Yards, 1 Rushing TDs
– Game: IND vs BUF, 42-26 Win
Best Running Back fantasy games
#5. Marshall Faulk, October 1, 1995
– Stats: 177 Rushing Yards, 3 Rushing TDs, 45 Receiving Yards
– Game: IND vs STL, 21-18 Win
#4. Edgerrin James, October 15, 2000
– Stats: 219 Rushing Yards, 3 Rushing TDs
– Game: IND vs SEA, 37-24 Win
#3. Joseph Addai, November 26, 2006
– Stats: 171 Rushing Yards, 4 Rushing TDs, 37 Receiving Yards
– Game: IND vs PHI, 45-21 Win
#2. Jonathan Taylor, November 9, 2025
– Stats: 244 Rushing Yards, 3 Rushing TDs, 42 Receiving Yards
– Game: IND vs ATL, 31-25 (OT) Win
#1. Jonathan Taylor, November 21, 2021
– Stats: 185 Rushing Yards, 4 Rushing TDs, 19 Receiving Yards, 1 Receiving TDs
– Game: IND vs BUF, 41-15 Win
Best Wide Receiver/Tight End fantasy games
#5. Marvin Harrison, November 25, 2004
– Stats: 127 Receiving Yards, 3 Receiving TDs, 12 Receptions, 16 Targets
– Game: IND vs DET, 41-9 Win
#4. Marvin Harrison, September 23, 2001
– Stats: 146 Receiving Yards, 3 Receiving TDs, 7 Receptions, 12 Targets
– Game: IND vs BUF, 42-26 Win
#3. Reggie Wayne, October 29, 2006
– Stats: 138 Receiving Yards, 3 Receiving TDs, 10 Receptions, 11 Targets
– Game: IND vs DEN, 34-31 Win
#2. Marvin Harrison, September 28, 2003
– Stats: 158 Receiving Yards, 3 Receiving TDs, 6 Receptions, 8 Targets
– Game: IND vs NOR, 55-21 Win
#1. Marvin Harrison, November 11, 2001
– Stats: 174 Receiving Yards, 3 Receiving TDs, 9 Receptions, 12 Targets
– Game: IND vs MIA, 24-27 Loss