INDIANAPOLIS — The Indianapolis Colts activated receiver Alec Pierce from the physically unable to perform list Thursday, two days before their final preseason game against the Detroit Lions.

Pierce had surgery on his left ankle in March after signing a four-year contract extension worth $114 million. He had a platelet-rich plasma injection, which uses a person’s blood to accelerate healing, prior to the start of free agency. But Pierce told reporters in June when that didn’t work after two months, he opted for surgery.