At M&T Bank Stadium on Monday, Derrick Henry and the Baltimore Ravens (1-1) meet Jared Goff and the Detroit Lions (1-1) in a battle featuring two of the biggest stars in the NFL on offense, beginning at 8:15 p.m. ET.
The Ravens knocked off the Cleveland Browns 41-17 in their last game. Against the Browns, Lamar Jackson led the Ravens with 225 yards on 19-of-29 passing (65.5%) for four touchdowns and no interceptions. Henry rushed for 23 yards on 11 carries (2.1 yards per carry). Zay Flowers led the receiving charge against the Browns, catching seven passes for 75 yards.
Their last time out, the Lions deefated the Chicago Bears 52-21. Goff totaled 334 passing yards while going 23-for-28 with five touchdowns and no interceptions for the Lions against the Bears. Jahmyr Gibbs carried the ball 12 times for 94 yards and one touchdown. He caught three passes for 10 yards. Amon-Ra St. Brown collected nine catches for 115 yards (on 11 targets), with three touchdowns.
See more information below, including how to watch this matchup on TV.
Ravens vs. Lions betting information
National Football League odds courtesy of BetMGM. Odds updated Friday at 11:28 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Ravens (-4.5)Moneyline: Ravens (-235), Lions (+195)Total: 53.5 pointsRavens betting insightsThe Ravens have covered the spread once this year.The Ravens have been favored by 4.5 points or more once this season and covered the spread.Ravens games this year have gone over the total in two out of two opportunities (100%).Lions betting insightsThe Lions have one win against the spread in two games this season.Lions contests this year have gone over the point total one time in two games (50%).
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Ravens leadersJackson: 434 PASS YDS / 217.0 YPG / 68.8% / 6 TD / 0 INT / 8 CAR / 83 RUSH YDS / 1 TDHenry: 29 CAR / 192 YDS / 96.0 YPG / 2 TD / 1 REC / 13 YDS / 6.5 YPG / 0 TDFlowers: 14 REC / 218 YDS / 109.0 YPG / 1 TDDeAndre Hopkins: 4 REC / 99 YDS / 49.5 YPG / 2 TDDevontez Walker: 2 REC / 26 YDS / 26.0 YPG / 2 TDNnamdi Madubuike: 7 TKL / 2.0 TFL / 2.0 SACKRoquan Smith: 25 TKL / 3.0 TFLNate Wiggins: 8 TKL / 1.0 TFL / 1 INT / 3 PDLions leadersGoff (QB): 559 YDS (80.6%) / 6 TD / 1 INTSt. Brown (WR): 13 REC / 160 YDS / 3 TD / 80.0 YPGGibbs (RB): 113 YDS / 1 TD / 56.5 YPG / 5.4 YPC / 13 REC / 41 REC YDS / 0 REC TD / 20.5 REC YPGJameson Williams (WR): 6 REC / 131 YDS / 1 TD / 65.5 YPGBrian Branch (DB): 11 TKL / 3.0 TFL / 1.0 SACKJack Campbell (LB): 17 TKL / 0.0 TFLTerrion Arnold (CB): 12 TKL / 0.0 TFLDerrick Barnes (LB): 12 TKL / 1.0 TFLRavens vs. Lions game infoGame day: Monday, September 22, 2025Game time: 8:15 p.m. ETLocation: Baltimore, MarylandStadium: M&T Bank StadiumTV channel: ABC/ESPNLive stream: Watch on Fubo! (Regional restrictions may apply)
Watch Baltimore Ravens vs. Detroit Lions on Fubo! (Regional restrictions may apply)