Check out these betting insights and trends before placing player prop wagers on Mac Jones for Sunday’s game, which starts at 4:25 p.m. ET on FOX. NFC West foes meet in Week 3 when Jones and the San Francisco 49ers (2-0) square off against the Arizona Cardinals (2-0) at Levi’s Stadium in Santa Clara, California.
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Mac Jones week 3 player propsMatchup: San Francisco 49ers vs. Arizona CardinalsTime: 4:25 p.m. ETDate: September 21, 2025Passing yards prop: Over 235.5 (-115)Rushing yards prop: Over 7.5 (-118)
National Football League odds courtesy of BetMGM. Odds updated Friday at 9:47 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Mac Jones passing stats and trendsLast season, Jones finished with 167.2 passing yards per game, lower than his prop bet over/under for this matchup (235.5).In 10 games played last season, he twice exceeded 235.5 passing yards in a single contest.Jones’ average passing yards prop last season was 207.1, while his per-game average fell short of that by 39.9 yards.Jones exceeded his passing yards prop bet total in four games last year, or 57.1% of games with a prop available.He had a passing touchdown in five of 10 games last year, with multiple passing TDs in three of them.Jones threw at least one interception in five of 10 games last season, including multiple INTs three times.49ers vs. Cardinals stats and trendsThe 216.1 yards per game the Cardinals conceded through the air last year made them the NFL’s 14th-ranked pass defense.Conceding 126.4 rushing yards per game last season, the Cardinals had the 20th-ranked run defense in the league.The 49ers made things happen on both sides of the ball in the passing game last year, as they ranked fourth-best in passing offense (249.1 passing yards per game) and fifth-best in passing defense (192.8 passing yards allowed per game).The 49ers ranked 12th in run offense (127.2 rushing yards per game) and 18th in run defense (124.6 rushing yards allowed per game) last year.The 49ers found success on both sides of the ball in terms of yards per play last season, ranking second-best in yards per play on offense (6.4) and fourth-best in yards per play allowed on defense (5.4).
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