The Buffalo Bills could be without three key players on Sunday when they host the New Orleans Saints.
Defensive tackle Ed Oliver, linebacker Matt Milano and offensive tackle Spencer Brown have all missed both practices so far this week.
Ed Oliver (ankle) watched practice off to the side today and was not wearing a protective boot.
Matt Milano (pectoral) and Spencer Brown (calf) were also not practicing during the media viewing portion.
AJ Epenesa (pectoral) was on the field practicing. #BillsMafia pic.twitter.com/Lb2UeOSfdJ
— Andy Young (@AndyYoungTV) September 25, 2025
Without Brown on the offensive line, Ryan Van Demark would be in line to make the start at right tackle against the Saints.
Van Demark started two games in place of Brown last season, and spent quite a bit of practice time working with the starters this summer.
The 27-year-old, now in his fourth season, feels prepared to step in and block for running back James Cook and protect MVP quarterback Josh Allen.
“Spencer missed some time during camp, so I got a lot of reps during camp and I have the chemistry with the ones o-line and Josh too,” said Van Demark. “I think I’m going to do great and it’ll be awesome, if Spencer can’t go.”
The Bills and Saints kick off Sunday at 1 p.m. at Highmark Stadium in Orchard Park.