Something will have to give when the streaking Houston Texans (0-3) meet the Tennessee Titans (0-3), who have lost three in a row, on Sunday, September 28, 2025 at NRG Stadium. Oddsmakers predict the game to be a competitive matchup with most books calling it a pick ’em. The over/under in the contest is set at 38.5 points.

In their last action, the Texans lost against the Jacksonville Jaguars, 17-10.

The Texans’ C.J. Stroud was 25-for-38 for 204 yards against the Jaguars, with one TD and two INTs.

The Titans lost versus the Indianapolis Colts in their last game, 41-20.

Texans vs Titans betting information

NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 8:03 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread favorite: Houston (-7.5)Moneyline: Houston (-394), Tennessee (+306)Total: 38.5 pointsTexans betting insightsAt home last season, Houston was 3-4-1 against the spread and 5-3 overall.The Texans are winless against the spread this season (0-3-0).At home last season, Houston was winless ATS (0-1) as 7.5-point favorites or more.In eight home games last year, Houston hit the over once.Games involving the Texans have yet to hit the over this season.Texans leadersStroud: 599 PASS YDS / 199.7 YPG / 64% / 2 TD / 3 INT / 13 CAR / 81 RUSH YDS / 0 TDNick Chubb: 34 CAR / 141 YDS / 47.0 YPG / 1 TD / 5 REC / 31 YDS / 10.3 YPG / 0 TDNico Collins: 14 REC / 181 YDS / 60.3 YPG / 2 TDDalton Schultz: 11 REC / 96 YDS / 32.0 YPG / 0 TDXavier Hutchinson: 7 REC / 75 YDS / 25.0 YPG / 0 TDTexans vs Titans game infoDate: Sunday, September 28, 2025Time: 1 p.m. ETCity: Houston, TexasVenue: NRG StadiumTV channel: CBSLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Paramount+ (Regional restrictions may apply)

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