SANTA CLARA, Calif. (AP) — The San Francisco 49ers have little time to focus on the four turnovers, leaky run defense and lack of a pass rush that contributed to their first loss of the season.

They have more pressing concerns starting with the health of quarterback Brock Purdy following a 26-21 loss to the Jacksonville Jaguars on Sunday leading into a short week.

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Coach Kyle Shanahan said Monday that Purdy reported after the game that he had soreness in the toe that sidelined him the previous two games. Purdy needed to undergo more tests to help determine his status this week when the Niners (3-1) visit the division rival Los Angeles Rams on Thursday night.

“Anytime guys are sore and hurting on a Monday, you usually don’t stress too much about it,” Shanahan said. “But, anytime you have a Thursday game, it’s a totally different element. So yeah, I’m concerned with anybody who’s not totally healthy at this moment.”

San Francisco has two other key players dealing with injuries with leading wide receiver Ricky Pearsall dealing with what Shanahan said was likely a minor PCL injury and receiver Jauan Jennings having sore ribs.

Shanahan said it’s hard to know if the toe injury impacted Purdy’s shaky performance against the Jaguars. He went 22 for 38 for 309 yards and two touchdowns but also threw two interceptions and lost a fumble on a potential game-winning drive.

Purdy was off-target on several passes, missing high on a few and throwing a little low and behind Jennings in the end zone on a potential touchdown.

“Anytime you miss a throw, we point out mechanics on every play, so mechanics go in and out,” Shanahan said. “Sometimes that can be overcompensating for an injury. Sometimes it’s just how you set your body and moving in the pocket and always trying to get your body in a position to have the right mechanics. So, there’s a lot of factors that go into it. That possibly could be the toe or possibly could be like any other day in the NFL.”

Extra points

CB Renardo Green (neck) has a chance to return this week after missing Sunday’s game. … Shanahan said the plan right now is to open S Malik Mustapha’s practice window after Week 6 as he tries to return from offseason knee surgery.

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