The Tampa Bay Buccaneers (3-1) visit the Seattle Seahawks (3-1) at Lumen Field in Seattle for a Week 5 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, October 5, including live updated odds and injury report news.

Seahawks vs. Buccaneers live odds, moneyline, over/under

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Seahawks vs. Buccaneers picks against the spread

Jon Hoefling: Tampa Bay Buccaneers (+3.5)

While I would not be shocked to see Seattle win this game, 3.5 points is a lot for a team that opened as the underdog. Seattle probably wins this one by a field goal.

Tyler Dragon: Tampa Bay Buccaneers (+3.5)

The Bucs are dealing with injuries but I expect them to get back on track this week in Seattle. Former Ohio State teammates Jaxon Smith-Njigba and Emeka Egbuka are two of the best young wideouts in the league.

Richard Morin: Tampa Bay Buccaneers (+3.5)

I’m not sold on the Seahawks yet. But Baker Mayfield? I’m buying those stocks.

Lorenzo Reyes: Seattle Seahawks (-3.5)

This is a sneaky good matchup, but I’m going to give the edge to Seattle because they’re at home, but more importantly because injuries are unfortunately piling up for Tampa Bay, especially on defense.

Blake Schuster: Tampa Bay Buccaneers (+3.5)

If you’re giving me the Bucs with points, I’m going to take the Bucs with points. Even without Mike Evans, this Tampa Bay team is real.

Christopher Bumbaca: Tampa Bay Buccaneers (+3.5)

The Seahawks are 3-7 against the spread the week after playing the Cardinals since 2018. Baker Mayfield is probably inventing some slight Sam Darnold made against him from their 2022 season with the Carolina Panthers.

Seahawks vs. Buccaneers updated injury reportNFL Week 5 picks, predictions oddsUSA TODAY NFL picks against the spread standingsNameWeek 42025 RecordBlake Schuster10-5-134-27-3Jon Hoefling7-8-133-28-3Tyler Dragon8-7-133-28-3Lorenzo Reyes5-10-130-31-3Chris Bumbaca6-9-130-31-3Jordan MendozaN/A24-22-2Richard Morin9-6-19-6-1Super Bowl 60 updated odds