Will Week 6 deliver an upset out of nowhere?

The day got off to a solid start as No. 14 Iowa State fell on the road to Cincinnati, though that can’t be called an upset since the Bearcats were actually favored to win the game.

Advertisement

What else does Week 6 have in store? After all, the biggest surprises usually come on weekends you’d least expect. Here’s how to watch college football this weekend; follow all of Saturday’s action below (scroll for live updates).

No. 9 Texas at Florida, 3:30 ET (ESPN)

A big day for Arch Manning can vault him back into the Heisman conversation ahead of the Red River Rivalry. And it could make things even worse in Gainesville. If Florida is going to pull the upset, the Gators have got to figure out how to score more than one touchdown.

No. 16 Vanderbilt at No. 10 Alabama, 3:30 ET (ABC)

The Commodores beat Alabama 40-35 a season ago in Nashville. Can Diego Pavia and Co. pull off another upset, this time on the road? Alabama has been been on a roll since its opening week loss to Florida State.

Advertisement

No. 3 Miami at No. 18 Florida State, 7:30 ET (ABC)

Florida State took some shine off this game with its loss to Virginia in Week 5. But the Seminoles now can’t afford to drop to 0-2 in the ACC if they want to make the College Football Playoff. It’s also a bounce-back opportunity for Carson Beck’s Heisman chances after a down game in Miami’s win over Florida.