Quarterback Kyler Murray was not on the Arizona Cardinals’ field for the open portion of practice on Thursday as he recovers from a foot injury.

Cardinals QB Jacoby Brissett leads the offense with Kyler Murray missing his second day of practice. pic.twitter.com/rEcpUnNDy1

— Tyler Drake (@Tdrake4sports) October 9, 2025

Head coach Jonathan Gannon told reporters on Wednesday, before Murray missed practice, that the quarterback is taking it “day-by-day” ahead of Sunday’s Week 6 matchup at the 4-1 Indianapolis Colts.

Murray briefly exited last Sunday’s loss against the Tennessee Titans after a play during which center Hjalte Froholdt snapped the ball into his facemask. Murray went to the locker room shortly after.

The Cardinals announced that Murray was questionable to return with a foot injury. Backup quarterback Jacoby Brissett took three snaps before Murray returned to the game.

Murray has not missed a game since the 2023 season when he returned from his ACL tear. In five games this year, Murray has completed 68.3% of his passes for 962 yards, six touchdowns and three interceptions. He has added 173 rushing yards on 29 attempts.

Brissett signed with Arizona this offseason to provide an experienced backup who started five games in 2024.

“If he’s gotta play, he’s gotta play,” Gannon said. 

Defensive end Darius Robinson was also a non-participant at practice for both Wednesday and Thursday as he continues to deal with a chest issue.

The second-year defender missed last week’s game against Tennessee after starting the first four weeks of the season. Robinson has five tackles and one sack so far.

The Cardinals added punter Blake Gillikin to the practice report Thursday for a back injury that limited him.

Player
Pos
Injury
Wednesday
Thursday
Friday
Game Status

Kelvin Beachum
OL
NIR-Rest
DNP
Full
–
–

Kyler Murray
QB
Foot
DNP
DNP
–
–

Darius Robinson
DL
Pectoral
DNP
DNP
–
–

Evan Brown
OL
Hamstring
Limited
Limited
–
–

Blake Gilikin
P
Back
–
Limited
–
–

Jonah Williams
OL
Foot
Limited
Limited
–
–

Cody Simon
LB
Knee
Limited
Limited
–
–

Mack Wilson Sr.
LB
Ankle
Limited
Limited
–
–

Will Hernandez
OL
Knee
Limited
Limited
–
–

Will Johnson
CB
Groin
Limited
Limited
–
–

Zay Jones
WR
Knee
Limited
Limited
–
–

Max Melton
CB
Hamstring
Limited
Limited
–
–

Here’s what the injury picture looks like for the Colts:

Player
Pos
Injury
Wednesday
Thursday
Friday
Game Status

Tyler Goodson
RB
Groin
DNP
DNP
–
–

Tyquan Lewis
DE
Illness
DNP
Full
–
–

Kenny Moore
CB
Achilles
DNP
DNP
–
–

Braden Smith
OT
NIR-Rest
DNP
Full
–
–

Alec Pierce
WR
Concussion
Full
Full
–
–

Grover Stewart
DT
Biceps
Full
DNP
–
–