AFC North opponents square off when the Pittsburgh Steelers (3-1) host the Cleveland Browns (1-4) on Sunday, October 12, 2025 at Acrisure Stadium. Pittsburgh is favored by 5.5 points.

Steelers vs. Browns game infoGame day: Sunday, October 12, 2025Game time: 1 p.m. ETTV channel: CBSLocation: Pittsburgh, PennsylvaniaStadium: Acrisure StadiumLive stream: Watch this game on Fubo (Regional restrictions may apply)Live stream: Watch this game on Paramount+ (Regional restrictions may apply)

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Steelers vs. Browns odds & betting linesSpread favorite: Pittsburgh (-5.5)Moneyline: Pittsburgh (-272), Cleveland (+220)Total: 38.5 points

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Steelers vs. Browns recent matchupsPittsburgh is 3-2 versus Cleveland over the last five matchups between the two teams.The Steelers and Browns haven’t gone over the total in any of their past five matchups, but Pittsburgh is 3-2 against the spread in those games.Pittsburgh outscored Cleveland 110-87 in those five head-to-head matchups.Steelers vs. Browns betting insightsPittsburgh has two wins against the spread so far this season (2-2-0). In three games as the moneyline favorite, the Steelers have gone 2-1. Cleveland, in five games with a set spread so far this season, is 2-3-0 against the spread. The Browns have been the moneyline underdog five times this year, going 1-4 in those games.Steelers scoring insightsLooking at the Steelers’ last three contests, they have generated 20.7 points per game on offense (22nd-ranked) and have allowed 22.0 points per game on defense (14th-ranked).Browns scoring insightsAt home, the Browns are averaging more points (15.3) than on the road (13.5).On defense, Cleveland’s average at home, 16.0 points conceded, is better than its average on the road, 37.5.The Browns are putting up 13.3 points per game in their past three games (second-worst in NFL), and conceding 21.7 per game (13th).Steelers injury reportSteelers:
Cameron Heyward: Did Not Participate In Practice (NIR – Rest),
T.J. Watt: Full Participation in Practice (NIR – Rest),
Alex Highsmith: Full Participation in Practice (Ankle),
Jaylen Warren: Full Participation in Practice (Knee),
Joey Porter Jr.: Full Participation in Practice (Hamstring),
Darius Slay: Full Participation in Practice (NIR – Rest),
Calvin Austin III: Did Not Participate In Practice (Shoulder),
Ben Skowronek: Full Participation in Practice (Illness),
Jalen Ramsey: Did Not Participate In Practice (Hamstring),
D.K. Metcalf: Did Not Participate In Practice (NIR – Rest)Browns injury reportBrowns:
Denzel Ward: Full Participation in Practice (Hip),
Raheim Sanders: Full Participation in Practice (Ankle),
Ethan Pocic: Full Participation in Practice (Neck),
David Njoku: Full Participation in Practice (Knee),
Kaitori Leveston: Limited Participation in Practice (Calf),
Shelby Harris: Limited Participation in Practice (Knee),
Damontae Kazee: Did Not Participate In Practice (Illness),
Jack Conklin: Limited Participation in Practice (Rest),
Michael Hall: Limited Participation in Practice (Knee),
Myles Garrett: Limited Participation in Practice (Ankle),
Grant Delpit: Full Participation in Practice (Ankle),
Maliek Collins: Full Participation in Practice (Rest),
Malachi Corley: Limited Participation in Practice (Groin),
Joel Bitonio: Full Participation in Practice (Rest)

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