Dan Johnson takes you through his preview, prediction, and pick for NFL Week 6’s game between the Jacksonville Jaguars and the Seattle Seahawks.

The air in Duval crackles throughout tailgates well before noon, because this one carries stakes that buzz through every seat before the stadium doors even open. The Jacksonville Jaguars ride in at 4-1 with three straight wins and a 3-0 home pulse. The Seattle Seahawks arrive 3-2, carrying a 2-0 road mark and a habit of quiet, ruthless travel. The market suggests balance—Seahawks -1.5, total 47.5, moneylines near -110 both ways—yet the matchup howls offense. These teams average 54.6 points per game combined, while allowing 41, and the building will feel it from the first snap. Jacksonville stands 4-1 against the spread, while Seattle sits 3-2 against the spread, which frames the coin-flip tone. Both teams are 3-2 to the over, and the opener at 44.5 swelled toward 47.5 as bettors leaned into points. The Jaguars have covered all three at home, while the Seahawks have covered six straight away and won nine of their last ten road games. Below is my prediction for NFL Week 6’s game between the Jacksonville Jaguars and the Seattle Seahawks.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Trevor Lawrence conducts a duet offense with Travis Etienne Jr. where the ground pulse powers everything. Jacksonville scores 25.4 points per game and churns 137.0 rushing yards, then turns play-action into sharp punctures. Lawrence completed 18 of 25 for 221 yards in Kansas City and then ripped 54 rushing yards with two touchdowns. His season sits at 1,066 yards, six touchdowns, and five interceptions on 60.4% completions with six sacks. That profile stabilizes when Etienne thunders for 443 rushing yards, 88.6 per game, and 5.8 per carry. He has three total touchdowns, including one through the air, which forces safeties to flinch. Jacksonville averages 5.4 yards per play and sustains tempo when the pocket stays tidy. They rank fifth in rushing and tenth in scoring, while the passing game sits at 205.6 yards. Lawrence’s legs keep third downs alive with 25 carries for 86 yards and two rushing scores. Etienne adds nine receptions for 41 yards, and Brian Thomas Jr. supplies 16 catches for 244 yards. Bhayshul Tuten spices the mix with 94 rushing yards and one rushing score, plus four grabs for 45 and another touchdown.

Sam Darnold operates a precision orchestra that makes space sing before defenses exhale. Seattle’s engine averages 29.2 points per game because he completes 73.1% and stacks 1,246 passing yards. Last week he went 28 of 34 for 341 yards and four touchdowns, the sound of a heater catching. Across five games he holds nine touchdowns against three interceptions, with only six sacks absorbed. He has 98 completions on 134 attempts, and he averages 9.3 yards per attempt. He also averages 249.2 passing yards per game and has topped 240 in nine of ten road starts. Jaxon Smith-Njigba sets the downfield tempo with 34 catches for 534 yards on 43 targets and two scores. He averages 106.8 yards on 6.8 catches per game and owns 500 yards on fewer than 40 receptions. Kenneth Walker III keeps boxes honest with 330 rushing yards, 4.9 per carry, and three touchdowns. Walker has seven receptions for 58 yards, the quiet valve that prevents overload. Seattle’s offense stamps 6.3 yards per play, ranks fifth in passing, and sits nineteenth on the ground.

This game tilts on philosophy: Seattle stonewalls the run, while Jacksonville weaponizes the ball in midair. The Seahawks allow 83.0 rushing yards per game and only two rushing touchdowns, then dare throws. They yield 239.8 passing yards with a 70.3% opponent completion rate, which invites calculated shots. They allow 322.8 total yards per game with 13 sacks and seven interceptions banked. Leonard Williams carries 2.5 sacks, and Ernest Jones stacks 40 tackles and two interceptions. Jacksonville counters by tightening the red zone and stealing possessions, allowing 20.0 points per game. They have forced 14 takeaways, the turn of the screw that flips fields and breath. Foyesade Oluokun anchors with 44 tackles, while Devin Lloyd owns four interceptions and a 99-yard touchdown. Arik Armstead adds 2.5 sacks, the shove that rattles timing when it matters. Jacksonville’s defense concedes 250.4 passing yards and 97.8 rushing yards per game, so opponents lean pass-heavy. That contrast turns every second-and-medium into a test of nerve and placement.

Availability redraws the map where the ball flies. Seattle lists Riq Woolen, Julian Love, and Devon Witherspoon doubtful, which strips matchup versatility and compresses leverage. That matters against Travis Hunter and Brian Thomas Jr., because Seattle already allows 239.8 passing yards on 70.3% completions. Jacksonville lists Robert Hainsey doubtful and places Brenton Strange on injured reserve, which weakens interior timing and red-zone structure. Travon Walker plans to play through a wrist cast, preserving edge pressure against Sam Darnold’s 73.1% precision. Net effect: the injuries tilt advantage toward Jacksonville’s boundary passing and toward a quicker, rhythm-based script. Seattle’s balance still travels, but those absences open targets the Jaguars can attack repeatedly. Expect a heavier air game and a small edge to Jacksonville.

Seahawks vs. Jaguars pick, best bet

Recent form tilts tempo upward. Jacksonville just won 31-28, with Lawrence punching the winner with 23 seconds left. Seattle lost 38-35 despite 463 total yards and five touchdowns. Both teams 3-2 to the over; Jacksonville games after wins have gone over in nine straight. Opponents throw against Jacksonville on 65.59% of snaps, and Seattle embraces air damage at 245.4 passing yards per game. Every split points toward space downfield and a scoreboard that refuses to idle. Seattle has topped 30 points in three of five, with 44 against New Orleans and 31 versus Pittsburgh fueling confidence. Jacksonville’s last two high-end opposing passers posted 318 and 309 passing yards, which underscores the aerial invitation. Seattle’s 21 of 27 record in 1 p.m. East Coast starts over the past decade also calms travel noise.

The counterargument soars from the runway, because the Seahawks are legitimate. Seattle has won nine of its last ten road games and sits 2-0 away this season. The Seahawks allow only 21.0 points per game and will wedge early downs with that 83.0 rush defense. Jacksonville plays on a short week, which often saps legs and rhythm. The refutation slams back with numbers that sting. Jacksonville sits 3-0 at home and 4-1 against the spread, with 48 points off turnovers already and a +8 turnover differential. Seattle’s differential sits at -1, and points off turnover margin has tilted the wrong way. That swing invites extra possessions, extra snaps, and extra breathless minutes for a secondary that limps. Seattle is 7-0 against the spread in its last seven Sunday games as a road underdog, but Jacksonville has covered four straight at home. The Jaguars have scored the first touchdown in eight of their last nine Sunday games, which lets that pass rush play downhill. Jacksonville’s rest disadvantage trend is ugly, yet turnovers can erase that drag when the ball keeps finding hands.

Seattle’s secondary limps into Duval, and the scheme invites what Jacksonville wants outside. Devon Witherspoon, Julian Love, and Riq Woolen sit doubtful, and the edges feel exposed. But the heartbeat stays binary: the Jaguars’ takeaways meet the Seahawks’ poise. Jacksonville has forced 14 takeaways and allows 20.0 points per game, the steady drum. Seattle counters with 29.2 points per game and Sam Darnold’s 73.1% precision, which cools panic. That balance should shield him from the greedy windows that Devin Lloyd has punished. Now the leverage point tilts to space: Travis Hunter’s vertical springs and Brian Thomas Jr.’s stride. Seattle’s coverage concedes 239.8 passing yards on 70.3% completions, and those lanes glitter. This profiles as Travis Hunter’s week, with equal runway for Brian Thomas Jr. to pop. Travis Etienne Jr. can still sting, but Seattle’s 83.0 rushing yards allowed narrows that alley. So Jacksonville must light the boundary and steal one more possession than Seattle’s rhythm allows. Expect points; these offenses combine for 54.6 per game, and the script invites fireworks.

I’m calling it now: this’ll be Travis Hunter’s first real NFL cosmic storm game. Get ready for a superstar statline. The play is the over 47.5, and my projection lands Jaguars 30, Seahawks 27, with Jacksonville claiming the final breath. So give them the ML lean in this current pick-em on DraftKings.

Best bet: Jaguars vs. Seahawks o47.5 total points (-110)

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For a prop lean, we’re riding Travis Hunter’s receiving ladder up to 50+ at +130 odds. As mentioned above—Seattle already gives up 239.8 passing yards on 70.3% completions, so windows widen when those three sit. Their front erases base runs at 83.0 rushing yards allowed and only two rushing touchdowns, so Jacksonville should throw with intent. That tilt feeds Travis Hunter 50+. Travis Hunter just flashed 64 yards last week and ripped a 44-yard shot when the game crackled. He sits at 16 receptions for 182 yards, and his burst stresses the exact coverage looks Seattle wants to play short-handed. Brian Thomas Jr.’s 244 yards on 16 catches will pull safety eyes, which frees Hunter to knife the sideline and punish rotated help. Trevor Lawrence just hit 72% on 18 of 25 in Kansas City, and Jacksonville averages 25.4 points per game, so volume meets efficiency here. We attack Hunter 50+ at plus money because the matchup funnels targets outside, the injuries sap Seattle’s disguise, and the run math pushes Jacksonville to the air.

Best prop lean: Travis Hunter 50+ receiving yards (+130)

Tail it with me in the DKN Betting Group here!