College football Week 7 straight-up picks
Week 7 picks include Indiana-Oregon, Alabama-Missouri, Texas-Oklahoma and more.
LOS ANGELES — College football blue bloods meet in the city of angels in Week 7, with No. 15 Michigan visiting Southern California in a Big Ten matchup.
The Wolverines and Trojans enter the contest with identical records − 4-1 with the loss to a ranked opponent. It’s not the end of the world, but not ideal for teams trying to position themselves in the College Football Playoff conversation, putting greater urgency in this game; win and get rewarded with a resume boost, lose and those postseason hopes drastically fade.
Lincoln Riley has one of the best offenses in the country, but USC’s defense hasn’t been as strong, which should excite Michigan quarterback Bryce Underwood and running back Justice Hayes to lead its deadly running game. Michigan got the upper hand against the Trojans last season in Ann Arbor, will it repeat on the West Coast or will Riley get a much-needed victory?
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TEAMS1Q2Q3Q4QSCOREMichigan077USC7714USC vs Michigan live updates
A touchdown just before halftime gives the Trojans a touchdown lead at the midway point of the contest.
USC receiver Makai Lemon makes an incredible touchdown catch to give the Trojans the lead. He is able to haul in a 12-yard pass to make it 14-7 with 14 second left in the first half.
The Wolverines are finally on the board. Bryce Underwood finds Donaven McCulley across the endzone for an 8-yard touchdown pass to tie the game at 7-7.
Michigan put up its best drive of the day with a 14-play, 86-yard march in just over six minutes. Much of the damage was done on the ground, something the Wolverines excel at.
Michigan gets into USC territory for the first time, but is unable to turn it into points. On a third down at the Trojan 32-yard line, Wolverines quarterback Bryce Underwood gets sacked for a loss of 11 yards, resulting in a Michigan punt.
The Trojans lead by a touchdown after the first 15 minutes of the contest.
USC went right down the field on its opening drive while Michigan went three-and-out afterward. The Trojans were again in position to score but a costly fumble in the red zone spoiled a promising drive. Now, the Wolverines are in Trojan territory with some momentum.
USC quarterback Jayden Maiava has been on fire with 101 yards and a touchdown on 10 of 11 passing. The Trojans are outgunned the Wolverines 138-52.
Just when it looks like the Trojans are close to scoring, tight end Lake McRee fumbles the ball at the Michigan 12-yard line. The turnover happened as Lyons was putting the finishing touches on what would’ve been a 21-yard gain and set USC up for a chance to make it a double-digit game.
McRee was questionable to play but started the game.
The Trojans march right down the field with an 11-play, six minute drive that’s capped by a 2-yard touchdown pass from Jayden Maiava to Ja’Kobi Lane to take an early 7-0 lead.
Maiava was perfect on the drive, going 4-for-4 for 46 yards.
Michigan wins the coin toss and defers to the second half.
What time does USC vs Michigan start? Date: Saturday, Oct. 11Time: 7:30 p.m. ET Where: Los Angeles Memorial Coliseum
USC and Michigan will kick off at 7:30 p.m. ET on Saturday, Oct. 11 from Los Angeles Memorial Coliseum in Los Angeles.
What TV channel is USC vs Michigan on today?
USC and Michigan will air nationally on NBC in Week 7 of the 2025 college football season. Streaming options include Peacock ― NBC’s streaming platform ― and Fubo, the latter of which offers a free trial to potential subscribers.
Stream Michigan vs. USC on Peacock
USC vs Michigan predictions, picks, odds
Odds courtesy of BetMGM as of Thursday, Oct. 9.
Spread: USC (-2.5)Over/under: 56.5Moneyline: USC (-130) ∣ Michigan (+105)Prediction: USC 24, Michigan 20 − The Trojan offense isn’t as explosive, but the defense steps up to make life difficult for Bryce Underwood to pick up a signature win at home.
Michigan
Brady Norton, OL – questionable
USC
Elijah Paige, OL – questionableLake McRee, TE – questionableAlex Graham, CB – questionable
Here is Michigan’s schedule and results.
Game 1: vs. New Mexico (W, 34-17)Game 2: at Oklahoma (L, 24-13)Game 3: vs. Michigan (W, 63-3)Game 4: at Nebraska (W, 30-27)Game 5: vs. Wisconsin (W, 24-10)Game 6: at USCGame 7: vs. WashingtonGame 8: at Michigan StateGame 9: vs. PurdueGame 10: at NorthwesternGame 11: at MarylandGame 12: vs. Ohio StateGame 1: vs. Missouri State (W, 73-13)Game 2: vs. Georgia Southern (W, 59-20)Game 3: at Purdue (W, 33-17)Game 4: vs. Michigan State (W, 45-31)Game 5: at Illinois (L, 34-32)Game 6: vs. MichiganGame 7: at Notre DameGame 8: at NebraskaGame 9: vs. NorthwesternGame 10: vs. IowaGame 11: at OregonGame 12: vs. UCLA
Michigan football will break out the “big game blues” against USC. The Wolverines uniform for the contest includes the traditional blue helmet, white jersey and blue pants. The pants are typically reserved for the biggest games of the season.
Saturday’s meeting will be the 12th time the Trojans and Wolverines meet on the gridiron. USC owns a 6-5 advantage in the series.
Of the previous 11 meetings, eight have taken place in the Rose Bowl Game. When meeting in the regular season, Michigan is 3-0 against USC, including last season’s 27-24 victory in Ann Arbor.
A star Trojan led the football team onto the field as women’s basketball guard JuJu Watkins emerged from the tunnel with USC. The star won’t play in the upcoming 2025-26 season as she recovers from an ACL injury, but she still is supporting her university.