Check out the injury report for the San Francisco 49ers (4-1), which features 17 players (including Mac Jones), as the 49ers ready for their matchup versus the Tampa Bay Buccaneers (4-1) at Raymond James Stadium, on Sunday, Oct. 12 at 4:25 p.m. ET.
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49ers vs Buccaneers TV channel & game infoGame day: Sunday, October 12, 2025Game time: 4:25 p.m. ETLocation: Tampa, FloridaStadium: Raymond James StadiumTV channel: CBSLive stream: Watch on Fubo! (Regional restrictions may apply)Live stream: Watch on Paramount+! (Regional restrictions may apply)
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49ers injury reportYetur Gross-Matos | DL (Out)Injury: KneePractice Status: Did Not Participate In PracticeRicky Pearsall | WR (Out)Injury: KneePractice Status: Did Not Participate In Practice2025 Receiving Stats: 29 Targets | 20 Receptions | 327 Yards | 0 TouchdownsBrock Purdy | QB (Out)Injury: ToePractice Status: Did Not Participate In Practice2025 Passing: 73-for-48 | 586 Yards | 4 Touchdowns | 4 InterceptionsJordan Watkins | WR (Out)Injury: CalfPractice Status: Did Not Participate In PracticeKevin Givens | DL (Out)Injury: PectoralPractice Status: Limited Participation in Practice2024 Defensive Performance: 3.5 Sacks | 2.0 Tackles for Loss | 11 Tackles | 0 Interceptions | 0 Passes DefendedKalia Davis | DL (Questionable)Injury: HandPractice Status: Limited Participation in PracticeUpton Stout | CB (Questionable)Injury: AnklePractice Status: Limited Participation in Practice2025 Defensive Stats: 1.0 Sack | 1.0 Tackles for Loss | 20 Tackles | 0 Interceptions | 2 Passes DefendedMac Jones | QB (Questionable)Injury: KneePractice Status: Limited Participation in Practice2025 Passing: 129-for-86 | 905 Yards | 6 Touchdowns | 1 InterceptionMalik Mustapha | S (Questionable)Injury: KneePractice Status: Full Participation in Practice2024 Defensive Performance: 0.0 Sacks | 2.0 Tackles for Loss | 71 Tackles | 1 Interception | 5 Passes DefendedAlfred Collins | DT (Questionable)Injury: KneePractice Status: Limited Participation in PracticeJauan Jennings | WR (Questionable)Injury: AnklePractice Status: Limited Participation in Practice2025 Receiving Stats: 19 Targets | 9 Receptions | 129 Yards | 1 TouchdownChristian McCaffrey | RBInjury: RestPractice Status: Full Participation in Practice2025 Rushing: 91 Attempts | 282 Yards | 0 Touchdowns2025 Receiving Stats: 52 Targets | 39 Receptions | 387 Yards | 3 TouchdownsKendrick Bourne | WRInjury: RibPractice Status: Full Participation in Practice2025 Receiving Stats: 24 Targets | 18 Receptions | 229 Yards | 0 TouchdownsThomas Morstead | PInjury: BackPractice Status: Full Participation in Practice2025 Season Stats: 5 Games PlayedTrent Williams | OTInjury: RestPractice Status: Full Participation in Practice2025 Season Stats: 2 Games PlayedMykel Williams | DLInjury: WristPractice Status: Full Participation in Practice2025 Defensive Stats: 0.0 Sacks | 3.0 Tackles for Loss | 10 Tackles | 0 Interceptions | 0 Passes DefendedCJ West | DTInjury: ThumbPractice Status: Full Participation in Practice2025 Defensive Stats: 0.0 Sacks | 0.0 Tackles for Loss | 2 Tackles | 0 Interceptions | 0 Passes Defended49ers insightsThe 49ers have put up slightly fewer points per game over their previous three matchups (21) than they have averaged for the season (21.2).Turning our focus to yardage, San Francisco has amassed slightly more total yards per game over its past three matchups (383.7) than it has averaged for the season (375.8).In the passing game, the 49ers have seen improved production over their last three games, collecting 307 passing yards per game, compared to their season-long average of 290.6 passing yards per contest.San Francisco has racked up slightly fewer rushing yards per game over its previous three matchups (76.7) than it has averaged for the season (85.2).49ers vs Buccaneers odds
NFL odds courtesy of BetMGM. Odds updated Saturday at 5:31 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread Favorite: Buccaneers (-3.5)Moneyline: Buccaneers (-180), 49ers (+149)Total: 47.5 points
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