Bills at Panthers odds, picks and predictions

The Buffalo Bills (4-2) and Carolina Panthers (4-3) meet Sunday for a Week 8 game at Bank of America Stadium in Charlotte,North Carolina. Kickoff is scheduled for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Bills vs. Panthers odds and make our expert NFL picks and predictions for the best bets.

The Bills lost 24-14 to the Atlanta Falcons on Monday night in Week 6 as a 4-point favorite on the road prior to the team’s bye in Week 7. QB Josh Allen had 180 passing yards and 2 TDs, but he also had 2 INTs. RB James Cook rushed for 87 yards. Buffalo has dropped 2 in a row, and it is 0-4 against the spread (ATS) since opening 2-0 ATS. The Under has cashed in each of the past 2 games, too, averaging 17.0 points per game (PPG), while allowing 23.5 PPG in the span.

The Panthers topped the New York Jets 13-6 on the road as a 1-point favorite as the Under (39.5) easily cashed. QB Bryce Young threw for 138 yards and a TD, but he suffered an ankle sprain, so backup QB Andy Dalton finished up and will start against the Bills with Young doubtful. RB Rico Dowdle ran for 79 yards and WR Xavier Legette posted 9 grabs for 92 yards and a TD. Carolina has won and covered 3 in a row, while the Over is 3-1 despite the Week 7 Under result. Carolina is also 5-1 ATS in the past 6 games.

The Bills beat the Panthers 31-14 the last time these teams met in 2021. The Bills lead the all-time series 6-2, going 2-1 in Carolina.

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Bills at Panthers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 8:26 p.m. ET.

Moneyline (ML): Bills -400 (bet $400 to win $100) | Panthers +310 (bet $100 to win $310)Against the spread: Bills -7 (-118) | Panthers +7 (-102)Over/Under (O/U): 46.5 (O: -110 | U: -110)

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Bills at Panthers key injuries

Bills

LB Terrel Bernard (ankle) questionableCB Maxwell Hairston (knee) questionableDT DaQuan Jones (calf) outTE Dalton Kincaid (oblique) questionableLB Matt Milano (pectoral) questionableWR Joshua Palmer (knee, ankle) outS Taylor Rapp (knee) out

Panthers

QB Bryce Young (ankle) doubtfulBills at Panthers picks and predictionsPrediction

Bills 26, Panthers 15

AVOID.

The Bills (-400) will set you back 4 times your potential return, and that’s way too much for a singular bet, even if you were to use a promo or boost. As part of a multi-leg parlay, it is too much risk to include Buffalo, too.

Look to the spread instead.

Back BILLS -7 (-118) to get back on track on the road.

Buffalo has some issues on defense, especially with Bernard carrying a questionable tag into the game. He is the team’s best cover man. But, Dalton is starting for the Panthers, not Young, and that could mess with the team’s chemistry as it looks to stay hot.

Buffalo is rested and raring to go, and it should cool off Carolina, who gets its biggest test to date.

UNDER 46.5 (-110) is a strong play. While Carolina has been a little better on offense, it should have issues with Dalton under center. Things are going to be disrupted.

For Buffalo, it has also struggled on offense. While it’s likely adjustments were made during the bye, the Panthers defense has been surprisingly decent lately. It has allowed 19.0 PPG in the past 3 games, including just 6 last week in a win against another AFC East team, the Jets.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Bills at Panthers odds, picks and predictions

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