The San Francisco 49ers (5-3) will play the New York Giants (2-6) on Sunday, November 2, 2025 at MetLife Stadium. The spread predicts a close game, with the 49ers favored by 2.5 points. The over/under is 48.5 in the outing.

The Giants lost to the Philadelphia Eagles, 38-20, in their last game.

In that matchup versus the Eagles, G-Men QB Jaxson Dart completed 14 of 24 attempts for 193 yards, with one touchdown and no interceptions.

The 49ers’ most recent game was against the Houston Texans, and they lost by a score of 26-15.

Giants vs 49ers betting information

NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 5:43 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread favorite: San Francisco (-2.5)Moneyline: San Francisco (-146), New York (+122)Total: 48.5 pointsGiants betting insightsNew York has covered the spread twice at home, and is 2-1 overall there, this season.The Giants have compiled a 4-4-0 record against the spread this year.At home, New York has two wins ATS (2-1) as 2.5-point underdogs or greater.The Giants are 4-3 ATS when playing as at least 2.5-point underdogs.This year, in three home games, New York has hit the over once.Games involving Giants have hit the over four times this year.Giants leadersDart: 984 PASS YDS / 140.6 YPG / 59.9% / 8 TD / 3 INT / 43 CAR / 195 RUSH YDS / 4 TDTyrone Tracy Jr.: 45 CAR / 159 YDS / 26.5 YPG / 1 TD / 10 REC / 68 YDS / 11.3 YPG / 0 TDWan’Dale Robinson: 38 REC / 494 YDS / 61.8 YPG / 2 TDTheo Johnson: 23 REC / 212 YDS / 26.5 YPG / 4 TDDaniel Bellinger: 11 REC / 194 YDS / 27.7 YPG / 1 TDGiants vs 49ers game infoDate: Sunday, November 2, 2025Time: 1 p.m. ETCity: East Rutherford, New JerseyVenue: MetLife StadiumTV channel: CBSLive stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on Paramount+ (Regional restrictions may apply)

Watch San Francisco 49ers vs. New York Giants on Fubo! (Regional restrictions may apply)