Colts at Chiefs odds, picks and predictions

The Indianapolis Colts (8-2) and Kansas City Chiefs (5-5) meet Sunday for a Week 12 game at GEHA Field at Arrowhead Stadium in Kansas City, Missouri. Kickoff is scheduled for 1 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Colts vs. Chiefs odds and make our expert NFL picks and predictions for the best bets.

The Colts lead the all-time series 18-10, including a 20-17 win at home in the most recent meeting in 2022. Indianapolis also won its last visit to Kansas City, posting a 19-13 victory in 2019. The last win for the Chiefs against the Colts was a 31-13 victory in an AFC Wild Card playoff game in Kansas City on Jan. 12, 2019.

Indy is coming off a 31-25 victory in overtime against the Atlanta Falcons in Berlin in Week 10, pushing at most shops as a 6-point favorite as the Over (48.5) cashed. RB Jonathan Taylor thrashed the Falcons for 244 rushing yards and 3 more TDs, including an 83-yard scamper for score. The Over is 4-1 in the past 5 games.

The Chiefs will be happy to be back home after suffering a 22-19 loss at the Denver Broncos in Week 11, failing as a 4.5-point favorite as the Under (45) cashed. QB Patrick Mahomes threw for 276 yards and a TD strike to TE Travis Kelce. Kansas City has lost and failed to cover the past 2 outings, while the Under has cashed in 5 in a row.

Watch the NFL on Fubo!

Colts at Chiefs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 7:57 p.m. ET.

Moneyline (ML): Colts +154 (bet $100 to win $154) | Chiefs -185 (bet $185 to win $100)Against the spread: Colts +3.5 (-118) | Chiefs -3.5 (-102)Over/Under (O/U): 49.5 (O: -110 | U: -110)

WIN YOUR FANTASY FOOTBALL LEAGUE! The Huddle has been turning players like you into winners for over 25 years. This season, it’s your turn. Custom fantasy football rankings, sleepers and tools are just a click away. Subscribe now!

Colts at Chiefs key injuries

Colts

LB Jaylon Carlies (ankle) outDE Tyquan Lewis (groin) questionableCB Charvarius Ward (concussion) questionable

Chiefs

RB Isiah Pacheco (knee) outOG Kingsley Suamataia (concussion) questionableWR Xavier Worthy (ankle) questionableColts at Chiefs picks and predictionsPrediction

Chiefs 23, Colts 20

The Chiefs (-185) will cost you nearly 2 times your potential return, and that’s a little too pricey for a standalone wager. However, if you were to use a boost or promo, or perhaps a no-sweat bet, that would be perfect OK. And, including Kansas City as part of a multi-leg parlay is quite all right, too.

PASS, and look to the spread instead.

Back the CHIEFS -3.5 (-102) laying the points at home. Kansas City has been championship-caliber for a long time, and we’ll see that championship mettle tested Sunday. It is a bit overplayed in sports, but this is truly a “must-win” game. The Chiefs cannot afford to slip a game under .500 heading into the final week of November, and it cannot take another loss to an AFC team in the playoff picture.

UNDER 49.5 (-110) is the way to go in this Week 12 AFC showdown.

The Under is on a 5-game run for the Chiefs, allowing 17 or fewer points in 3 of the past 5 games. The Chiefs are allowing 14.8 points per game in that 5-game span. The Chiefs are middle of the road in rushing defense, allowing exactly 1,000 rushing yards this season, and 4.2 yards per carry. However, Kansas City has allowed just 1 run of 20+ yards, so Taylor and the Colts might not be able to put up quick scores like they’ve done in recent weeks.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @danieledobish on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

Colts at Chiefs odds, picks and predictions

Tags: