The Buffalo Bills (7-4) visit the Pittsburgh Steelers (6-5) at Acrisure Stadium in Pittsburgh for a Week 13 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, November 30, including live updated odds and injury report news.
NameWeek 122025 SeasonJon Hoefling5-8-189-85-4Blake Schuster4-9-187-74-4Tyler Dragon6-7-188-86-4Chris Bumbaca5-8-183-91-4Lorenzo Reyes5-8-182-92-4Jordan Mendoza4-9-168-77-3Richard MorinN/A25-12-1Steelers vs. Bills live odds, moneyline, over/under
Opening Lines
Spread: Bills (-4.5)Moneyline: Bills (-218), Steelers (+180)Over/Under: 46.5
Get the edge with our exclusive NFL betting picks
Steelers vs. Bills picks against the spreadTyler Dragon: Buffalo Bills (-3.5)
T.J. Watt and the Steelers defense are licking their chops after Josh Allen was sacked eight times last week. Allen and the Bills survive in Pittsburgh.
Jon Hoefling: Buffalo Bills (-3.5)
Sure the Bills have looked off as of late but are we really going to pick 40-year-old Rodgers to beat Josh Allen? Come on. Lets be serious.
Blake Schuster: Pittsburgh Steelers (+3.5)
This might be a mistake, but I still refuse to fade Mike Tomlin as a home underdog. I’ll stick with the trend that’s paid out consistently.
Jordan Mendoza: Buffalo Bills (-3.5)
The road hasn’t been kind to Buffalo recently, which makes this feel like the Steelers will have this. Josh Allen turns it around in this one.
Lorenzo Reyes: Buffalo Bills (-3.5)
Check the status of Aaron Rodgers here, but the Bills should bounce back here. Buffalo struggles against the better defenses in the NFL, and Pittsburgh is not that.
Richard Morin: Buffalo Bills (-3.5)
The Steelers are too focused on looking in the AFC North rearview at the suddenly surging Ravens and newly energized Bengals. The Bills deal them a sucker punch here.
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