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The Tennessee Titans and San Francisco 49ers play on Sunday, Dec. 14, at the 49ers’ Levi’s Stadium in a game on the NFL Week 15 schedule.
Which team will win the NFL Week 15 game?
Check out these NFL Week 15 picks and NFL Week 15 predictions for the game, which can be seen at 2:25 p.m. MST on FOX (stream with FUBO).
The 49ers are a 12.5-point favorite over the Titans in NFL Week 15 odds for the game, courtesy of BetMGM Sportsbook.
San Francisco is -1000 on the moneyline, while Tennessee is +650. The over/under (point total) is set at 44.5 points.
NFL Week 15 picks: Falcons at Buccaneers | Browns at Bears | Ravens at Bengals | Cardinals at Texans | Jets at Jaguars | Chargers at Chiefs | Bills at Patriots | Commanders at Giants | Raiders at Eagles | Packers at Broncos | Lions at Rams | Panthers at Saints | Colts at Seahawks | Titans at 49ers | Vikings at Cowboys | Dolphins at Steelers | The Republic’s picks
Watch Titans at 49ers live on FUBO (free trial)
Jeremy Cluff writes: “Can the Titans start a win streak against the 49ers? Don’t count on it. Brock Purdy and company will jump on Tennessee early on their way to their 10th win of the season.”
Bookies.com: Bet the over in 49ers vs Titans game
Bill Speros writes: “There’s no reason for anyone outside San Francisco to watch this game unless it involves a multi-leg parlay (Why?) or fantasy play. The Titans somehow beat Cleveland Sunday, putting their quest for the No. 1 overall pick in peril. The rested-and-getting-healthier Niners come off the bye – and get another bye. Brock Purdy and the 49ers begin to rediscover their mojo this week. But don’t touch this line with your ex-Mother-In-Law’s money.”
The site’s formula predicts that the 49ers will win the NFL Week 15 game against the Titans.
ESPN: 49ers have an 82.7% chance to beat Titans on Sunday
The site gives the Titans a 17.2% shot at winning the NFL Week 15 game, with the remaining percentage accounting for a tie.
Dimers: 49ers 28, Titans 16
It writes: “After extensive simulations, our model gives the Titans a win probability of 14%, while the 49ers have a win probability of 86%.”
Sportsnaut: San Francisco 49ers 24, Tennessee Titans 13
Matt Johnson writes: “The San Francisco 49ers should have little trouble dispatching the Tennessee Titans in Week 15. Christian McCaffrey is a near-lock for 110-plus scrimmage yards and a score, all the while Brock Purdy and George Kittle should put up some good numbers. There’s not much analysis really necessary; this is a top-10 team versus a Titans club that should arguably be winless this season.”
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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
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