When the San Francisco 49ers (9-4) host the Tennessee Titans (2-11) on Sunday, December 14, 2025 at Levi’s Stadium, they will be aiming to extend their three-game winning streak.
How to watch Tennessee Titans vs. San Francisco 49ersTennessee vs. San Francisco odds
Injury reports49ers
No injuries listed
Titans
No injuries listed
Stats to know
The 49ers are averaging 3.9 fewer points per game (23.6) than the Titans are allowing (27.5).
Tennessee’s defense has surrendered an average of 350.9 yards per game this season, just 9.7 yards more than the 341.2 San Francisco’s offense has averaged. SF picks up 5.5 yards per play, while Tennessee allows 6.1.
The Titans’ average points scored this year, 15.5, is 5.2 fewer than the 20.7 the 49ers are giving up.
San Francisco’s defense has surrendered 335.8 yards per game in 2025, 89.6 yards more than the 246.2 Tennessee’s offense has averaged. Tennessee gains 4.7 yards per play and San Francisco gives up 5.7.
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