The Houston Texans (8-5) take a five-game winning streak into their contest with the Arizona Cardinals (3-10) on Sunday, December 14, 2025 at NRG Stadium. The Texans are considerable favorites in this one, with the spread sitting at 10.5 points. An over/under of 42.5 points has been set for the contest.
The Cardinals’ last game was against the Los Angeles Rams, and they lost by a score of 45-17.
Against the Rams, Jacoby Brissett completed 25 of 44 attempts for 271 yards, with two touchdowns and one interception, for the Cards.
The Texans beat the Kansas City Chiefs, 20-10, in their last game.
Cardinals vs Texans betting information
NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 8:59 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread favorite: Houston (-10.5)Moneyline: Houston (-578), Arizona (+431)Total: 42.5 pointsCardinals betting insightsArizona is 2-4 overall, and 5-1 against the spread, in away games.The Cardinals have covered the spread six times over 13 games with a set spread.Arizona has hit the over twice in six road games this year.Cardinals games have finished with a final combined score above the over/under eight times this season.Cardinals leadersBrissett: 2,459 PASS YDS / 245.9 YPG / 66.2% / 15 TD / 5 INT / 31 CAR / 138 RUSH YDS / 1 TDBam Knight: 81 CAR / 271 YDS / 24.6 YPG / 4 TD / 22 REC / 160 YDS / 14.5 YPG / 1 TDEmari Demercado: 31 CAR / 241 YDS / 30.1 YPG / 0 TD / 8 REC / 64 YDS / 8 YPG / 1 TDTrey McBride: 93 REC / 937 YDS / 72.1 YPG / 8 TDMichael Wilson: 61 REC / 712 YDS / 54.8 YPG / 3 TDMarvin Harrison Jr.: 40 REC / 594 YDS / 59.4 YPG / 4 TDCardinals vs Texans game infoDate: Sunday, December 14, 2025Time: 1 p.m. ETCity: Houston, TexasVenue: NRG StadiumTV channel: FOXLive stream: Watch on Fubo (Regional restrictions may apply)
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