The San Francisco 49ers (9-4) host the Tennessee Titans (2-11) on Sunday, December 14, 2025 at Levi’s Stadium and will aim to continue a three-game winning streak.

What channel is 49ers vs. Titans on?Location: Levi’s Stadium in Santa Clara, CaliforniaDate: Dec. 14Time: 4:25 p.m. ETTV channel: FOXLive stream: Fubo (Regional restrictions may apply)Live stream: Sling

Watch 49ers vs. Titans LIVE on Fubo! (Regional restrictions may apply)

What time is 49ers vs. Titans?

The 49ers and the Titans play at 4:25 p.m. ET.

49ers vs. Titans betting odds, lines, spread

The latest odds can be found below:

49ers vs. Titans updated injury report

View up-to-the-minute playing status of both teams’ injured players below:

49ers vs. Titans recent matchupsSan Francisco and Tennessee have been evenly matched over their last two matchups, sharing the same 1-1 record.Over their last two head-to-head matchups, Tennessee has scored 43 points, while San Francisco has tallied 42.12/23/2021: Titans 20, 49ers 1712/17/2017: 49ers 25, Titans 23

Watch 49ers vs. Titans LIVE with Fubo (Regional restrictions may apply)

49ers scheduleWeekDateOpponentTime (ET)TV ChannelLive Stream/Result1Sept. 7@ Seahawks—-Win, 17-132Sept. 14@ Saints—-Win, 26-213Sept. 21vs. Cardinals—-Win, 16-154Sept. 28vs. Jaguars—-Loss, 26-215Oct. 2@ Rams—-Win, 26-236Oct. 12@ Buccaneers—-Loss, 30-197Oct. 19vs. Falcons—-Win, 20-108Oct. 26@ Texans—-Loss, 26-159Nov. 2@ Giants—-Win, 34-2410Nov. 9vs. Rams—-Loss, 42-2611Nov. 16@ Cardinals—-Win, 41-2212Nov. 24vs. Panthers—-Win, 20-913Nov. 30@ Browns—-Win, 26-815Dec. 14vs. Titans4:25 p.m. ETFOXFubo | Sling16Dec. 22@ Colts8:15 p.m. ETESPNFubo | Sling17Dec. 28vs. Bears8:20 p.m. ETNBC/Peacock–18TBDvs. SeahawksTBDTBD–Titans scheduleWeekDateOpponentTime (ET)TV ChannelLive Stream/Result1Sept. 7@ Broncos—-Loss, 20-122Sept. 14vs. Rams—-Loss, 33-193Sept. 21vs. Colts—-Loss, 41-204Sept. 28@ Texans—-Loss, 26-05Oct. 5@ Cardinals—-Win, 22-216Oct. 12@ Raiders—-Loss, 20-107Oct. 19vs. Patriots—-Loss, 31-138Oct. 26@ Colts—-Loss, 38-149Nov. 2vs. Chargers—-Loss, 27-2011Nov. 16vs. Texans—-Loss, 16-1312Nov. 23vs. Seahawks—-Loss, 30-2413Nov. 30vs. Jaguars—-Loss, 25-314Dec. 7@ Browns—-Win, 31-2915Dec. 14@ 49ers4:25 p.m. ETFOXFubo | Sling16Dec. 21vs. Chiefs1 p.m. ETCBSParamount+ | Fubo17Dec. 28vs. Saints1 p.m. ETCBSParamount+ | Fubo18TBD@ JaguarsTBDTBD–NFL week 15 schedule

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