The Indianapolis Colts host the San Francisco 49ers on “Monday Night Football” in NFL Week 16 action. Both teams are watching injuries in the wake of Week 15 games.

The Colts, who are without right tackle Braden Smith (concussion, injured reserve), may be without left tackle Bernhard Raimann (elbow). Cornerback Sauce Gardner (calf) has missed the past two games, and defensive tackle DeForest Buckner (neck) and quarterback Anthony Richardson (eye) are eligible to come off injured reserve.

San Francisco wide receiver Ricky Pearsall left after its first play from scrimmage with an ankle issue, but he returned and had 6 catches for 96 yards.

Both teams have lost players for the rest of the regular season. For the Colts, quarterback Daniel Jones (Achilles) and cornerback Charvarius Ward (concussion); for the Niners, linebacker Fred Warner (ankle), defensive end Nick Bosa (knee) and wide receiver Brandon Aiyuk (knee).

Colts injuries to watchT Bernhard Raimann

Left tackle Bernhard Raimann (right elbow) left the game against the Seahawks and did not return.

CB Sauce Gardner

Cornerback Sauce Gardner (calf) left early in the Colts’ Week 13 game against the Houston Texans and has missed two games.

DT DeForest Buckner

Defensive tackle DeForest Buckner (neck) practiced during Week 15 but was not activated off injured reserve. He last played in Week 9.

WR Anthony Gould

Wide receiver/special teamer Anthony Gould (foot) missed Week 15 after suffering an injury in Week 14.

49ers injuries to watchWR Ricky Pearsall

Wide receiver Ricky Pearsall left after the Niners’ first play from scrimmage with an ankle issue, but he returned and had 6 catches for 96 yards.

DT Jordan Elliott

Defensive tackle Jordan Elliott (knee) was inactive against the Titans.

LB Tatum Bethune

Linebacker Tatum Bethune (ankle) was inactive against the Titans.

LB Nick Martin

Linebacker Nick Martin (concussion) was inactive against the Titans.

DE Sam Okuayinonu

Defensive end Sam Okuayinonu (ankle) was inactive against the Titans.

Colts injured reserveRB Salvon AhmedDT DeForest BucknerWR Ashton DulinT Blake FreelandQB Daniel JonesCB Chris LammonsWR D.J. MontgomeryLB Jacob PhillipsQB Anthony RichardsonS Daniel ScottK Spencer ShraderT Braden SmithCB Justin WalleyCB Charvarius WardT Jack WilsonS Hunter Wohler49ers injured reserveOL Ben BartchDL Nick BosaWR Jacob CowingDL Yetur Gross-MatosDL Tarron JacksonCB Jakob RobinsonRB Patrick Taylor Jr.WR Trent TaylorCB Tre TomlinsonLB Fred WarnerDL Mykel Williams49ers reserve/non-football injuryReserve/PUP

Joel A. Erickson and Nathan Brown cover the Colts all season. Get more coverage on IndyStarTV and with the Colts Insider newsletter.