The Tampa Bay Buccaneers (7-7) visit the Carolina Panthers (7-7) on Sunday, December 21, 2025 in matchup between NFC South rivals at Bank of America Stadium. Carolina is a 3-point underdog.

Buccaneers vs. Panthers game infoGame day: Sunday, December 21, 2025Game time: 1 p.m. ETTV channel: FOXLocation: Charlotte, North CarolinaStadium: Bank of America StadiumLive stream: Watch this game on Fubo (Regional restrictions may apply)

Watch Tampa Bay Buccaneers vs. Carolina Panthers on Fubo! (Regional restrictions may apply)

Buccaneers vs. Panthers odds & betting linesSpread favorite: Tampa Bay (-3)Moneyline: Tampa Bay (-159), Carolina (+133)Total: 45.5 points

NFL odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Buccaneers vs. Panthers recent matchupsTampa Bay has gone 5-0 versus Carolina over the last five matchups between the two teams.The Buccaneers and Panthers haven’t gone over the total in any of their past five matchups, but Tampa Bay is 3-2 against the spread in those games.Tampa Bay has had the upper hand scoring in those five matchups, totaling 134 points against Carolina’s 79.Buccaneers vs. Panthers betting insightsTampa Bay has five wins against the spread this season (5-9-0). In eight games as a moneyline favorite, the Buccaneers are 5-3. Carolina has eight wins against the spread in 14 opportunities this season (8-6-0). The Panthers are 7-5 in games they have played as the moneyline underdog.Buccaneers scoring insightsThe Buccaneers are averaging more points at home (25.0) than away (21.7).On defense, Tampa Bay’s average at home, 25.0 points conceded, is slightly better than its average away, 25.6.The Buccaneers are scoring 23.5 points per game in divisional contests, which is a little better than their 23.3 average in non-division games.Tampa Bay has allowed 19.0 points per game in the division, which is lower than its average in non-division games of 27.8.Looking at the Buccaneers’ last three contests, they have posted 22.7 points per game on offense (15th-ranked) and have surrendered 23.3 points per game on defense (16th-ranked).Panthers scoring insightsAt home, the Panthers are averaging more points (22.3) than away (16.3).On defense, Carolina is conceding 22.7 points per game at home, slightly more than its 22.6 average away from home.On offense, the Panthers average more points in division games (21.0) than non-division games (18.0).Carolina averages fewer points conceded in division games (16.0) than outside the division (25.3).The Panthers are 25th in the league in points scored for the past three games (19.0 per game) and 14th in points conceded (22.7).Buccaneers injury reportBuccaneers:
Lavonte David: Limited Participation in Practice (Knee),
Rashad Wisdom: Full Participation in Practice (Quad),
Tykee Smith: Full Participation in Practice (Neck),
Chris Godwin: Did Not Participate In Practice (Fibula),
SirVocea Dennis: Full Participation in Practice (Hip),
Cade Otton: Full Participation in Practice (Knee),
Mike Evans: Did Not Participate In Practice (Collarbone)Panthers injury reportPanthers:
Trevin Wallace: Limited Participation in Practice (Shoulder),
Taylor Moton: Limited Participation in Practice (Back),
David Moore: Full Participation in Practice (Elbow),
Jaycee Horn: Full Participation in Practice (NIR – Rest),
Tetairoa McMillan: Full Participation in Practice (Foot),
Damien Lewis: Limited Participation in Practice (Illness),
Tershawn Wharton: Did Not Participate In Practice (Hamstring),
Ikem Ekwonu: Did Not Participate In Practice (Knee)

Watch Tampa Bay Buccaneers vs. Carolina Panthers on Fubo! (Regional restrictions may apply)