The Atlanta Falcons (5-9) visit the Arizona Cardinals (3-11) Sunday in Week 16. Kickoff from State Farm Stadium in Glendale, Arizona, is at 4:05 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Falcons vs. Cardinals odds and make our expert NFL picks and predictions for the best bets.

The Falcons have lost 7 of their last 9 games, but snapped a 2-game losing streak Thursday night in Week 15, beating the Tampa Bay Buccaneers 29-28 on the road as 6.5-point underdogs with the Over (43) cashing. QB Kirk Cousins threw 3 TD passes and K Zane Gonzalez made a 43-yard field goal as time expired for the win.

The Cardinals lead the Falcons 18-16 all-time, including a win in the postseason. They last met in 2023, a 25-23 Cardinals win at home as 2-point underdogs with the Over (43.5) cashing.

Arizona won the last meeting 25-23 in 2023 and leads the all-time series 18-16.

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Falcons at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 6:28 p.m. ET.

Moneyline (ML): Falcons -160 (bet $160 to win $100) | Cardinals +135 (bet $100 to win $135)Against the spread (ATS): Falcons -3 (-102) | Cardinals +3 (-118)Over/Under (O/U): 48 (O: -110 | U: -110)Falcons at Cardinals key injuries

Falcons

DT Brandon Dorlus (illness, shoulder) questionableWR KhaDarel Hodge (shoulder) outCB Mike Hughes (ankle) outWR Drake London (knee) questionableLB James Pearce (foot) questionable

Cardinals

OL Evan Brown (personal) outDL L.J. Collier (knee) questionableWR Marvin Harrison Jr. (heel) questionableOL Paris Johnson (knee) outCB Max Melton (heel) outLB Cody Simon (knee, ankle) questionableS Dadrion Taylor-Demerson (ankle) questionableS Jalen Thompson (hamstring) outWR Xavier Weaver (hamstring) questionableFalcons at Cardinals picks and predictionsPrediction

Falcons 27, Cardinals 23

The Cardinals have lost 6 straight games and 11 of their last 12 games. They have lost 4 times in their last 6 by at least 3 scores, allowing 40 or more points in those games. They don’t stop the run or opposing top receivers, and they haven’t had a takeaway in their last 3 games.

The Falcons have scored 24 or more points in 5 of their last 6 games, and the Cardinals have not scored more than 20 points offensively in their last 4, and haven’t scored more than 22 in their last 6 games.

At this point, you just can count on the Cardinals, but the spread gives you better odds for the Falcons.

PASS.

The Cardinals are 1-5 ATS in their last 6 games and have lost by at least 3 points in all of their last 8 losses.

The Falcons are 5-0 ATS in their 5 wins.

BET FALCONS -3 (-102).

The Over is 5-1 in the Cardinals’ last 6 games and 8-2 in their last 10. The Cardinals have allowed 27 or more points in 7 of their last 9.

The Falcons have allowed 24 or more in 7 of their last 8.

BET OVER 48 (-110).

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