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Lions’ playoff hopes fade after gut-wrenching loss vs. Steelers

USA TODAY Sports’ Prince Grimes ‘overreacts’ to some of the best games from Sunday’s Week 16 slate.

The New Orleans Saints and Tennessee Titans play on Dec. 28 at the Titans’ Nissan Stadium in a game on the NFL Week 17 schedule.

Which team will win the NFL Week 17 game?

Check out these NFL Week 17 picks and NFL Week 17 predictions for the game, which can be seen at 11 a.m. MST on CBS (stream with FUBO).

The Saints are a 2.5-point favorite over the Titans in NFL Week 17 odds for the game, courtesy of BetMGM Sportsbook.

New Orleans is -145 on the moneyline, while Tennessee is +120. The over/under (point total) is set at 39.5 points.

NFL Week 17 picks: Cowboys at Commanders | Lions at Vikings | Broncos at Chiefs | Texans at Chargers | Ravens at Packers | Seahawks at Panthers | Cardinals at Bengals | Steelers at Browns | Jaguars at Colts | Buccaneers at Dolphins | Patriots at Jets | Saints at Titans | Giants at Raiders | Eagles at Bills | Bears at 49ers | Rams at Falcons | The Republic’s score predictions

Watch Saints at Titans live on FUBO (free trial)

Jeremy Cluff writes: “Tyler Shough continues to impress for the Saints, who have won three games in a row. New Orleans will make it four in a row with a big win in Tennessee.”

Bookies.com: Bet the Saints to cover vs Titans

Bill Speros writes: “The Titans desperately need a bounce-back loss to remain alive for the No. 1 draft pick. They picked apart remnants of the Chiefs in Week 16. New Orleans scored an upset road win at Tampa Bay 3 weeks ago. Rainy and unseasonably warm conditions await in Nashville. A perfect menu for one of the most unwatchable games of the season.”

The site’s formula predicts that the Saints will win the NFL Week 17 game against the Titans.

ESPN: Saints have a 55.9% chance to beat Titans on Sunday

The site gives the Titans a 43.8% shot at winning the NFL Week 17 game, with the remaining percentage accounting for a tie.

Dimers: Saints 21, Titans 18

It writes: “After extensive simulations, our model gives the Saints a win probability of 60%, while the Titans have a win probability of 40%.”

Sportsnaut: New Orleans Saints 24, Tennessee Titans 20

Matt Johnson writes: “The New Orleans Saints are rolling right now, riding a three-game winning streak with a +30 point differential. Defensively, the success dates back even further, as this unit has allowed just 15.8 points per game over its last six contests. While the Tennessee Titans have shown a bit more life as of late, the better roster and coaching staff will pull this one out to make it four consecutive victories.”

NFL’s highest paid players in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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