Quarterback Brock Purdy threw a career-high five touchdown passes as the San Francisco 49ers beat the Indianapolis Colts 48-27 to keep their NFC West title hopes alive.
The 25-year-old completed 25 of his 34 passes for 295 yards as the 49ers extended their winning streak to five matches.
Running back Christian McCaffrey caught two of the touchdown passes as the 49ers saw off a spirited Colts side.
Purdy became the first 49ers quarterback to throw five touchdowns in a game since the legendary Joe Montana in 1990.
The 49ers head into their final two regular-season matches – against the Chicago Bears and NFC West leaders the Seattle Seahawks – knowing two victories will secure the divisional title and home advantage in the play-offs.
The Colts’ fifth consecutive defeat means they drop out of the AFC South title race – although they could still secure a wildcard spot.
The result also guarantees post-season qualification for the Buffalo Bills, the Jacksonville Jaguars and the Los Angeles Chargers.