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Arizona Cardinals succeed at losing their 7th in a row

Injuries continue to pile up for the Arizona Cardinals as they wrap up their home schedule for the 2025 season.

The Arizona Cardinals and Cincinnati Bengals play on Sunday, Dec. 28, at the Bengals’ Paycor Stadium in a game on the NFL Week 17 schedule.

Which team will win the NFL Week 17 game?

Check out these NFL Week 17 picks and NFL Week 17 predictions for the game, which can be seen at 11 a.m. MST on FOX (stream with FUBO).

The Bengals are a 7-point favorite over the Cardinals in NFL Week 17 odds for the game, courtesy of BetMGM Sportsbook.

Cincinnati is -325 on the moneyline, while Arizona is +260. The over/under (point total) is set at 53.5 points.

NFL Week 17 picks: Cowboys at Commanders | Lions at Vikings | Broncos at Chiefs | Texans at Chargers | Ravens at Packers | Seahawks at Panthers | Cardinals at Bengals | Steelers at Browns | Jaguars at Colts | Buccaneers at Dolphins | Patriots at Jets | Saints at Titans | Giants at Raiders | Eagles at Bills | Bears at 49ers | Rams at Falcons | The Republic’s score predictions

Watch Cardinals at Bengals live on FUBO (free trial)

Jeremy Cluff writes: “Jacoby Brissett and the Cardinals have lost seven games in a row. Arizona’s offense won’t be able to keep up with Joe Burrow and Cincinnati, resulting in an eighth straight loss.”

Bookies.com: Bet the under in Bengals vs Cardinals game

Bill Speros writes: “The Cardinals entered full-tailspin mode with their 7th straight defeat in Week 16. It came in non-effort 26-19 aviary-on-aviary loss to the Falcons. This time, felines reign in Cincinnati. While the Bengals win this, we’re not so comfortable with a 7-point line. Cincy has failed to cover in 5 straight at home against NFC opponents. A mild-for-Ohio winter day eliminates weather as a factor here. But we’re not sure how these teams will get to 53.5 points. Maybe they play an extra 4 quarters?”

The site’s formula predicts that the Cardinals will win the NFL Week 17 game against the Bengals.

ESPN: Bengals have a 66.1% chance to beat Cardinals on Sunday

The site gives the Cardinals a 33.6% shot at winning the NFL Week 17 game, with the remaining percentage accounting for a tie.

Dimers: Bengals 28, Cardinals 23

It writes: “After extensive simulations, our model gives the Cardinals a win probability of 34%, while the Bengals have a win probability of 66%.”

Sportsnaut: Cincinnati Bengals 35, Arizona Cardinals 28

Matt Johnson writes: “There should be plenty of scoring on Sunday between the Cincinnati Bengals and Arizona Cardinals. Already fielding a bottom-10 defense, Arizona lost two key players (Garrett Williams and Walter Nolen) to season-ending injuries this past week. Meanwhile, the Bengals have had one of the league’s worst defenses all year, and they rank 32nd in the NFL versus tight ends. It should be a shootout in Cincinnati, but the better quarterback pulls it out.”

NFL’s highest paid players in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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