The Arizona Cardinals (3-13) visit the Los Angeles Rams (11-5) at SoFi Stadium in Inglewood for a Week 18 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, January 4, including live updated odds and injury report news.
NameWeek 172025 SeasonBlake Schuster3-12-1130-106-7Jon Hoefling9-6-1126-123-7Tyler Dragon6-9-1122-127-7Chris Bumbaca7-8-1108-112-6Lorenzo Reyes4-11-1111-123-6Jordan Mendoza7-8-1105-115-6Richard MorinN/A47-34-3Rams vs. Cardinals live odds, moneyline, over/under
Opening Lines
Spread: Rams (-4.5)Moneyline: Rams (-218), Cardinals (+180)Over/Under: 45.5
Get the edge with our exclusive NFL betting picks
Rams vs. Cardinals picks against the spreadJon Hoefling: Arizona Cardinals (+7.5)
Los Angeles didn’t look great on Monday night, and now they don’t have much to play for.
Tyler Dragon: Los Angeles Rams (-7.5)
The Rams end their two game losing streak against a lowly Cardinals team.
Christopher Bumbaca: Los Angeles Rams (-7.5)
The Rams’ falloff over the last couple weeks must be examined further. But the Cardinals can be sort of get-right opponent.
Jordan Mendoza: Los Angeles Rams (-7.5)
The Rams need to play their starters to prove they are ready for the playoffs. Playing against an Arizona team that has had plenty of blowout losses, Los Angeles cruises past this one.
Lorenzo Reyes: Los Angeles Rams (-7.5)
The Rams have hit a skid, though they still can fight for seeding in the NFC. They should treat this as a chance to lock in and course correct before the postseason.
Blake Schuster: Los Angeles Rams (-7.5)
Don’t worry, Cardinals fans. This season is nearly done. You can soon forget it ever happened and look forward to next year.
Rams vs. Cardinals updated injury reportNFL Week 18 picks, predictions, oddsSuper Bowl 60 updated odds