James Cook is really good. So is the Jaguars’ defense.
Those elements are the core perhaps the No. 1 matchup in Jaguars-Bills Sunday, with the Bills and running back James Cook entering as the NFL’s No. 1 running offense and the Jaguars entering as the NFL’s No. 1 rushing defense.
It’s strength versus strength – and Cook, the NFL’s leading rusher in 2025, is really strong.
“He’s an elite back,” Campanile said.
Cook, a fourth-year veteran, rushed for 1,621 yards and 12 touchdowns this season for a Bills offense that rushed for 159.6 yards per game. The Jaguars allowed 85.6 yards per game and did not allow a runner to rush for more than 75 yards in a game.
“They challenge you in so many ways with their run game,” Campanile said. “They make everybody tackle. They do a really good job in their combinations. They do a good job playing with their hands as an offensive line. Their perimeter does a really good job blocking. That’s generated a lot of their runs downfield.
“It’s a challenge at every level of the defense.”