Broncos vs. Bills spread, line, over/under

NFL Divisional Round odds: Broncos vs. Bills spread, line, over/under

The AFC Divisional round of the 2025 NFL Playoffs features a matchup between the Buffalo Bills (who are only 1.5-point underdogs) and the Denver Broncos on January 17, 2026 at 4:30 p.m. ET on .

Broncos vs. Bills game infoGame day: Saturday, January 17, 2026Game time: 4:30 p.m. ETLocation: Denver, ColoradoStadium: Empower Field at Mile HighLive stream: Watch this game on Fubo (Regional restrictions may apply)Watch Denver Broncos vs. Buffalo Bills on Fubo! (Regional restrictions may apply)Broncos vs. Bills odds & betting linesSpread favorite: Denver (-1.5)Moneyline: Denver (-117), Buffalo (-102)Total: 46 pointsExpert NFL picks: Exclusive betting insights only at USA TODAY.

NFL odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 10:56 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Broncos vs. Bills recent matchupsThe last four matchups between these two teams have resulted in a Dallas victory three times.Buffalo has had the upper hand scoring in those four matchups, totaling 99 points while Denver scored 50.Broncos vs. Bills betting insightsDenver has seven wins against the spread through 17 opportunities this season (7-10-0). In the 12 games this season the Broncos have been the moneyline favorite, they have put together a 10-2 record. Buffalo has eight wins against the spread this season (8-9-0). This is the third game this year the Bills are the moneyline underdog. They won both of the games.Broncos scoring insightsThe Broncos put up 25.6 points per game at home, better than their 21.4 average on the road.On defense, Denver allows fewer points at home (17.8 per game) than away (18.9).The Broncos have put up 19.2 points per game in the division, below their average against the rest of the league of 26.0.Denver averages fewer points allowed in division games (13.7) than outside the division (20.8).The Broncos rank 17th in scoring offense (19.7 points per game) and sixth in scoring defense (16.7 points per game allowed) over their most recent three-game stretch.Bills scoring insightsAt home, the Bills are averaging more points (31.2) than on the road (25.0).On defense, Buffalo is giving up 23.4 points per game at home, more than its 19.3 average on the road.On offense, the Bills have scored 27.3 points per game in the division, not as good as their average against the rest of the league of 28.8.Buffalo has given up 20.5 points per game in the division, which is better than its mark in non-division games of 22.0.The Bills are 11th in the NFL in points scored for the past three games (24.7 per game) and fourth-best in points allowed (15.0).Broncos injury reportBroncos: Drew Sanders: Limited Participation in Practice (Ankle), Lucas Krull: Limited Participation in Practice (Foot), Dre Greenlaw: Limited Participation in Practice (Hamstring), John Franklin-Myers: Full Participation in Practice (Hip)Bills injury reportBills: Damar Hamlin: Full Participation in Practice (Pectoral), Maxwell Hairston: Did Not Participate In Practice (Ankle), Terrel Bernard: Limited Participation in Practice (Calf), A.J. Epenesa: Limited Participation in Practice (Neck), Josh Allen: Full Participation in Practice (Foot), Tyrell Shavers: Did Not Participate In Practice (Knee), Curtis Samuel: Full Participation in Practice (Elbow), Greg Rousseau: Limited Participation in Practice (Back), Shaq Thompson: Limited Participation in Practice (Neck), Matt Prater: Full Participation in Practice (Quad), Jordan Poyer: Did Not Participate In Practice (Hamstring), Ed Oliver: Limited Participation in Practice (Biceps), Matt Milano: Limited Participation in Practice (Ankle), Dalton Kincaid: Limited Participation in Practice (Knee), Ty Johnson: Did Not Participate In Practice (Ankle)Watch Denver Broncos vs. Buffalo Bills on Fubo! (Regional restrictions may apply)

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