The first game in the Divisional Round of the 2026 NFL playoffs will feature an AFC matchup between the No. Buffalo Bills and the No. 1 Denver Broncos.

The Bills lead the all-time regular season series between these teams, 22-17-1, and the postseason series, 2-0. They most recently faced off in the AFC wild card round just a year ago in January 2025, with Buffalo winning at home, 31-7, to advance. The Broncos have had a much different journey to the playoffs this year, and were able to secure a first-round bye and home-field advantage as the No. 1 seed.

Here’s everything you need to know about the game:

Buffalo Bills vs. Denver Broncos

Game time: 4:30 PM EST
Channel: CBS
Online Streaming: FuboTV | Paramount+
Location: Empower Field at Mile High | Denver, CO
Announcers: Jim Nantz, Tony Romo, Tracy Wolfson (field reporter)

Buffalo Bills: +1.5 (+102)
Denver Broncos: -1.5 (120)
Over/under: 45.5 points

Open thread: Discuss Saturday’s game in the comments below.