San Francisco 49ers at Indianapolis Colts (2025-REG-16)

Local Radio coverage: Monday’s game can be heard in Indianapolis on 97.1 HANK FM and the Ascension St…

San Francisco 49ers quarterback Brock Purdy has been named the NFC Offensive Player of the Week following his…

McCaffrey Reaches 1,000 (Again) Running back Christian McCaffrey reached the 1,000-yard rushing mark for the season, finishing with…

Taylor is averaging 3.7 yards per rush over the last four weeks after averaging 6.0 yards per rush…

The San Francisco 49ers are back in primetime for their Week 16 contest against the Indianapolis Colts. The…

The Faithful had questions, and I’ve got the answers. Each week throughout the season, fans will have the…

As the San Francisco 49ers prepare for a crucial Week 16 ‘Monday Night Football’ showdown against the Indianapolis…

Indiana Nights will take center stage as the Colts host Monday Night Football at Lucas Oil Stadium. Monday’s…

Where to watch San Francisco 49ers at Indianapolis Colts? The week 16 game kicks off at 8:15 p.m. ET this Monday and is available to watch on ESPN.