{"id":1000807,"date":"2026-09-14T19:00:18","date_gmt":"2026-09-14T19:00:18","guid":{"rendered":"https:\/\/www.rawchili.com\/nfl\/1000807\/"},"modified":"2026-09-14T19:00:18","modified_gmt":"2026-09-14T19:00:18","slug":"buffalo-bills-vs-detroit-lions-week-2-fanduel-nfl-opening-odds","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/nfl\/1000807\/","title":{"rendered":"Buffalo Bills vs. Detroit Lions, Week 2 FanDuel NFL opening odds"},"content":{"rendered":"<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">The Buffalo Bills and Detroit Lions are set to face off in just a few days, opening Week 2 of the 2026 NFL season as the featured game to kick off Thursday Night Football on Prime Video. Both teams are 1-0 and coming off intense matchups that took every bit of luck and execution going their way.<\/p>\n<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">Now, Buffalo welcomes Detroit to the new Highmark Stadium for the first regular-season game in the team\u2019s new home, and in what should be a raucous, college-like atmosphere in primetime.<\/p>\n<p>What are the odds: Bills vs. Lions, NFL Week 2<\/p>\n<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">We\u2019ll only have to wait until late Thursday to find out it oddsmakers have this one figured accurately or not. There\u2019s a kinship between Buffalo and Detroit as two proud rustbelt franchises that have an affinity for blue-collar attitudes, but also a far too familiar relationship with heartbreak.<\/p>\n<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">Though each have found success in professional football from several generations ago, the Bills and Lions have yet to win a Super Bowl. In fact, Detroit has never played in a post-merger championship. Buffalo hasn\u2019t played in the Super Bowl since the last of their four consecutive appearances to close out the 1993 season.<\/p>\n<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">This will be the third time quarterback Josh Allen faces the Lions, dating back to the 2022 NFL season. Buffalo won both prior meetings, with the first taking place on Thanksgiving Day in November of 2022. Thursday\u2019s game marks the first time Allen gets to play a home game against Detroit.<\/p>\n<p>What happened in the last game between the Bills and Lions?<\/p>\n<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">The last time Buffalo and Detroit faced off, NFL fans were treated to an all-time classic shootout. The Bills ultimately won 48-42, with Allen throwing for 362 yards and a two touchdowns, adding 68 rush yards and another pair of touchdown jaunts. Running back James Cook III was also a huge force on the ground, finishing with 105 rushing yards and two scores as a ball carrier.<\/p>\n<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">Quarterback Jared Goff had one of the finest games of his career, finishing with 494 passing yards and five touchdowns through the air. Goff\u2019s favorite target that day, wide receiver Amon-Ra St. Brown caught 14 passes for 193 yards and one touchdown.<\/p>\n<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">Will the latest Bills-Lions matchup provide similar fireworks on Thursday? Don\u2019t bet against the odds of a similar game unfolding in primetime!<\/p>\n<p class=\"duet--article--dangerously-set-cms-markup duet--article--standard-paragraph _1upudxki _174s0un1 _174s0un0 _1mt21p01\">Think you\u2019ve got what it takes to make a play with the Buffalo Bills this season? Head to <a href=\"https:\/\/sportsbook.fanduel.com\/navigation\/nfl\" rel=\"nofollow noopener\" target=\"_blank\">FanDuel Sportsbook<\/a> to get started now!<\/p>\n","protected":false},"excerpt":{"rendered":"The Buffalo Bills and Detroit Lions are set to face off in just a few days, opening Week&hellip;\n","protected":false},"author":2,"featured_media":1000808,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2048],"tags":[215,214,53,15958,2086,7,6],"class_list":["post-1000807","post","type-post","status-publish","format-standard","has-post-thumbnail","category-buffalo-bills","tag-bills","tag-buffalo","tag-buffalo-bills","tag-buffalo-bills-odds","tag-buffalobills","tag-football","tag-nfl"],"share_on_mastodon":{"url":"https:\/\/channels.im\/@nfl\/117270939201939979","error":""},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/1000807","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/comments?post=1000807"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/1000807\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media\/1000808"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media?parent=1000807"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/categories?post=1000807"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/tags?post=1000807"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}