{"id":326688,"date":"2025-08-29T14:52:11","date_gmt":"2025-08-29T14:52:11","guid":{"rendered":"https:\/\/www.rawchili.com\/nfl\/326688\/"},"modified":"2025-08-29T14:52:11","modified_gmt":"2025-08-29T14:52:11","slug":"2025-week-1-college-football-betting-picks-odds-lines-this-saturday-college-football-parlay-pays-nearly-6-1","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/nfl\/326688\/","title":{"rendered":"2025 Week 1 college football betting picks, odds, lines: This Saturday college football parlay pays nearly 6-1"},"content":{"rendered":"<p>The Week 1 college football schedule is loaded with marquee matchups like No. 3 Ohio State (-1) vs. No. 1 Texas, No. 4 Clemson (-4) vs. No. 9 LSU and No. 10 Miami (+2.5) vs. No. 6 Notre Dame. However, building a winning college football parlay can be a challenge early in the season with so much roster turnover inherent in the modern era of the sport. Having a little help scouring the Week 1 college football odds can give you a head start in building winning college football betting tickets. The Over has been a trendy play recently in both Irish games and in Hurricanes games, with the total being surpassed in eight of Notre Dame&#8217;s last 12 games and 12 of Miami&#8217;s last 16.\u00a0<\/p>\n<p>That&#8217;s one reason why Over 49.5 points in Notre Dame vs. Miami is one of our top Week 1 college football predictions and a crucial piece of our Week 1 college football parlay. The Week 1 college football schedule began on Thursday night and continues through Monday night. Before locking in your Week 1 college football picks on your favorite <a href=\"https:\/\/www.cbssports.com\/betting\/news\/best-betting-apps\/\" target=\"_blank\" rel=\"nofollow noopener\">betting apps<\/a>, be sure to check out the top college football\u00a0<a href=\"https:\/\/www.cbssports.com\/betting\/\" target=\"_blank\" rel=\"nofollow noopener\">betting<\/a>\u00a0picks from SportsLine&#8217;s proven computer model. Claim the latest <a href=\"https:\/\/www.cbssports.com\/betting\/news\/bet365-promo-code\/\" target=\"_blank\" rel=\"nofollow noopener\">bet365 promo code<\/a> here, where new users <a href=\"https:\/\/martech.cbssports.com\/bt\/redirect\/prod?b=bet365&amp;c=sport\" target=\"_blank\" rel=\"nofollow noopener\" class=\"mtech-link\">get $200 in bonus bets with the placement of a $5+ bet:<\/a>\u00a0<\/p>\n<p>The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and was a profitable 27-16 combined on money-line and over\/under\u00a0<a href=\"https:\/\/www.sportsline.com\/college-football\/picks\/\" target=\"_blank\" rel=\"nofollow noopener\">college football picks<\/a>\u00a0in 2024. Anybody following its\u00a0<a href=\"https:\/\/www.cbssports.com\/betting\/news\/college-football\/\" target=\"_blank\" rel=\"nofollow noopener\">college football betting<\/a>\u00a0picks on\u00a0<a href=\"https:\/\/www.cbssports.com\/betting\/news\/best-betting-apps\/\" target=\"_blank\" rel=\"nofollow noopener\">betting sites<\/a>\u00a0could have seen strong returns, and new users can also target the\u00a0<a href=\"https:\/\/www.cbssports.com\/betting\/news\/draftkings-promo-code\/\" rel=\"nofollow noopener\" target=\"_blank\">DraftKings promo code<\/a>, which offers\u00a0<a href=\"https:\/\/martech.cbssports.com\/bt\/redirect\/prod?b=draftkings&amp;c=sport\" target=\"_blank\" rel=\"nofollow noopener\" class=\"mtech-link\">$300 in bonus bets instantly plus over $200 off NFL Sunday Ticket<\/a>:<\/p>\n<p>Best Week 1 college football parlay:\u00a0<\/p>\n<p>Combining the model&#8217;s three picks into a Week 1 college football parlay would result in a payout of +597 (risk $100 to win $597).<\/p>\n<p>Missouri State +35.5 vs. USC (-115)<\/p>\n<p>USC won 11 games in Lincoln Riley&#8217;s first season at the helm in 2022, but it&#8217;s been downhill from there. The Trojans won eight games in 2023 and then seven in 2024, and now Riley&#8217;s seat may be one of the hottest in the country. USC would like to use this game as a tune up for a grueling Big Ten schedule, but Missouri State isn&#8217;t likely to see it that way. The Bears are entering their first season in the FBS after accepting a bid to join Conference USA and a moral victory would go a long way towards putting the program on the map. The model predicts that Missouri State covers in 60% of simulations.<\/p>\n<p>Over 47.5 in Louisiana vs. Rice (-105)<\/p>\n<p>The Ragin Cajuns are coming off their fourth 10-win season in six years while Rice will look to turn the page with Scott Abell as its new head coach after he spent the last seven years at <a class=\"Annotation-link\" href=\"https:\/\/www.cbssports.com\/college-football\/teams\/DAVID\/davidson-wildcats\/\" rel=\"nofollow noopener\" target=\"_blank\">Davidson<\/a> (FCS). These two programs are at completely different stages of existence with Louisiana hoping to work their way into contention for the non-power conference bid to the CFP while Rice is starting over. The model expects Louisiana to do most of the scoring here, and predicts that the over hits in 68% of simulations.<\/p>\n<p>Over 49.5 points in Miami vs. Notre Dame (-110)<\/p>\n<p>Both teams will usher in new starting quarterbacks after Riley Leonard and Cam Ward both moved on to the NFL. However, there&#8217;s considerably more confidence on the Miami side with <a class=\"Annotation-link\" href=\"https:\/\/www.cbssports.com\/college-football\/players\/3163129\/carson-beck\/\" rel=\"nofollow noopener\" target=\"_blank\">Carson Beck<\/a> winning two national championship as a backup at <a class=\"Annotation-link\" href=\"https:\/\/www.cbssports.com\/college-football\/teams\/UGA\/georgia-bulldogs\/\" rel=\"nofollow noopener\" target=\"_blank\">Georgia<\/a> and then throwing for 7,426 yards and 52 touchdowns there in two seasons as a starter. Beck should have the Miami offense humming out of the gate while <a class=\"Annotation-link\" href=\"https:\/\/www.cbssports.com\/college-football\/players\/29388474\/cj-carr\/\" rel=\"nofollow noopener\" target=\"_blank\">CJ Carr<\/a> was a top-50 prospect coming out of high school and has prototypical size and arm strength. The model predicts that both have their moments and that the over hits in 69% of simulations.<\/p>\n<p>Want more Week 1 college football picks?<\/p>\n<p>You&#8217;ve seen the model&#8217;s Week 1 college football best parlay. Now, <a href=\"https:\/\/www.sportsline.com\/college-football\/picks\/#ttag=08302025_agg_cbssports_picks_football_CFB_model_Week1CFBbestparlay\" target=\"_blank\" rel=\"nofollow noopener\">get against the spread, total and money-line picks for every Week 1 CFB game here, all from the model that&#8217;s simulated every game 10,000 times<\/a>.\u00a0<\/p>\n<p>Also at SportsLine:<\/p>\n<p>You can also see Week 1 college football picks from legendary college football handicapper Bruce Marshall.\u00a0<a href=\"https:\/\/www.sportsline.com\/experts\/51297150\/bruce-marshall\/?league=cfb#ttag=08302025_agg_cbssports_picks_football_CFB_model_Week1CFBbestparlay\" target=\"_blank\" rel=\"nofollow noopener\">Visit SportsLine to see his best bets<\/a>. SportsLine&#8217;s Emory Hunt, who is 45-32 in his last 77 college football picks, has locked in his <a href=\"https:\/\/www.sportsline.com\/experts\/16030\/emory-hunt\/?league=cfb#ttag=08302025_agg_cbssports_picks_football_CFB_model_Week1CFBbestparlay\" target=\"_blank\" rel=\"nofollow noopener\">best bet for Oregon State vs. California right here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"The Week 1 college football schedule is loaded with marquee matchups like No. 3 Ohio State (-1) vs.&hellip;\n","protected":false},"author":2,"featured_media":326689,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[1107,331,7,21209,26726,38256,49,48,4732,21177,8242],"class_list":{"0":"post-326688","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-ncaa-football","8":"tag-betting","9":"tag-college-football","10":"tag-football","11":"tag-louisiana-ragin-cajuns","12":"tag-miami-fla-hurricanes","13":"tag-missouri-state-bears","14":"tag-ncaa","15":"tag-ncaa-football","16":"tag-notre-dame-fighting-irish","17":"tag-rice-owls","18":"tag-usc-trojans"},"share_on_mastodon":{"url":"https:\/\/channels.im\/@nfl\/115112623766239770","error":""},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/326688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/comments?post=326688"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/326688\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media\/326689"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media?parent=326688"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/categories?post=326688"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/tags?post=326688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}