The Indianapolis Colts open their 2025 season at home against the Miami Dolphins on Sunday, with plenty of attention on new quarterback Daniel Jones. Veteran teammates like Jonathan Taylor have praised Jones for his command of the offense and his ability to adjust at the line of scrimmage, noting how his leadership has set the tone in the huddle throughout the offseason. That presence will be critical as the Colts look to start strong against one of the AFC\u2019s most explosive teams.<\/p>\n
Oddsmakers see this game as a virtual coin flip. The Colts are slight 1.5-point favorites at Lucas Oil Stadium, while both teams sit at -108 on the moneyline. According to Dimers.com\u2019s predictive model<\/a>, Indianapolis has a 55% chance of victory after 10,000 simulations, with a projected 23-22 final score. The spread and total of 46.5 points each carry a 50-50 probability of hitting, underscoring how evenly matched these sides appear.<\/p>\n For the Dolphins, Tua Tagovailoa and Tyreek Hill headline a fast-paced offense that will test the Colts\u2019 secondary, while De\u2019Von Achane offers a big-play threat on the ground. Indianapolis counters with Taylor and wideouts Michael Pittman Jr. and Josh Downs, as Jones makes his debut in blue and white. Kickoff is set for 1 p.m. ET, and with both teams aiming to make early noise in the AFC, this opener carries plenty of intrigue.<\/p>\n Dolphins vs. Colts betting preview<\/p>\n Utilize the interactive widget below to see the latest spread, over\/under, and moneyline odds and probabilities for the Dolphins-Colts matchup at Lucas Oil Stadium.<\/p>\n This prediction and best bet for Sunday\u2019s NFL matchup between the Dolphins and Colts is from Dimers.com<\/a>, a reliable source for sports betting predictions.<\/p>\n Check out all the important details on today\u2019s game, as well as the best odds sourced from the top sportsbooks in the country.<\/p>\n Game details<\/p>\n The key information you need before the Dolphins vs. Colts NFL game.<\/p>\n Teams:\u00a0Miami Dolphins<\/a>\u00a0vs.\u00a0Indianapolis Colts<\/a>Date:\u00a0Sunday, September 7, 2025Kickoff:\u00a01 p.m. ETLocation:\u00a0Lucas Oil StadiumNFL standings:\u00a0Current NFL division standings<\/a>NFL injuries:\u00a0Check the latest updates to the official NFL injury report<\/a>Odds<\/p>\n The latest and best odds for the NFL matchup between the Dolphins and Colts.<\/p>\n Spread:\u00a0Dolphins +1.5 (-118), Colts -1.5 (-102)Moneyline:\u00a0Dolphins -108, Colts -108Total:\u00a0Over\/Under 46.5 (-110\/-105)<\/p>\n The odds and lines featured here are the best available from selected sports betting sites at the time of publication and are subject to change.<\/p>\n Promos<\/p>\n Note: Football fans in Indiana can use the Bet365 bonus code \u201cSYRACUSE\u201d<\/a> to unlock NFL betting deals.<\/p>\n Expert prediction: Dolphins vs. Colts<\/p>\n Using state-of-the-art data analysis and machine learning, the experts at Dimers have executed 10,000 simulations of Sunday\u2019s Dolphins vs. Colts<\/a> game.<\/p>\n According to Dimers\u2019 famous predictive analytics model, the Colts are more likely to beat the Dolphins at Lucas Oil Stadium. This prediction is based on the model giving the Colts a 55% chance of winning the game.<\/p>\n Furthermore, Dimers predicts that the bookies have gotten it right and the Dolphins and Colts each have a 50% chance of covering the spread, while the over\/under total of 46.5 points is also considered an equal 50-50 chance of hitting.<\/p>\n As always, these predictions and probabilities are correct at the time of publication but are subject to potential changes.<\/p>\n Dolphins vs. Colts best bet<\/p>\n Our top pick for the Dolphins vs. Colts Week 1 NFL matchup is to bet on the Colts moneyline (-108).<\/p>\n This betting advice is based on detailed modeling and valuable wagering intelligence, designed to assist you in making smarter decisions.<\/p>\n Score prediction for Dolphins vs. Colts<\/p>\n Dimers\u2019 predicted final score for the Miami vs. Indianapolis game on Sunday has the Colts winning 23-22.<\/p>\n This expert prediction is based on each team\u2019s average score following 10,000 game simulations, offering a glimpse into the potential outcome.<\/p>\n NFL player props: Sunday<\/p>\n NFL prop picks are a great way to wager on Sunday\u2019s game without necessarily betting on its outcome.<\/p>\n This article features the most likely first and anytime touchdown scorers for the Dolphins and Colts, along with projected player stats.<\/p>\n Miami DolphinsFirst touchdown scorer predictionsDe\u2019Von Achane:\u00a014.5% probabilityTyreek Hill:\u00a08.5% probabilityOllie Gordon:\u00a06.6% probabilityAnytime touchdown predictionsDe\u2019Von Achane:\u00a055.5% probabilityTyreek Hill:\u00a037.9% probabilityOllie Gordon:\u00a030.6% probabilityProjected box score leadersQB passing yards:\u00a0Tua Tagovailoa, 249 yardsReceiving yards:\u00a0Tyreek Hill, 73 yardsRushing yards:\u00a0De\u2019Von Achane, 62 yardsIndianapolis ColtsFirst touchdown scorer predictionsJonathan Taylor:\u00a015.0% probabilityMichael Pittman:\u00a05.3% probabilityJosh Downs:\u00a05.2% probabilityAnytime touchdown predictionsJonathan Taylor:\u00a056.4% probabilityMichael Pittman:\u00a025.5% probabilityJosh Downs:\u00a024.8% probabilityProjected box score leadersQB passing yards:\u00a0Daniel Jones, 213 yardsReceiving yards:\u00a0Josh Downs, 52 yardsRushing yards:\u00a0Jonathan Taylor, 83 yardsNFL Week 1: Dolphins vs. Colts<\/p>\n Get ready for Sunday\u2019s action between the Dolphins and Colts in Week 1 of the National Football League<\/a> season at Lucas Oil Stadium, which is scheduled to start at 1 p.m. ET. We emphasize that all of the NFL best bets and NFL predictions on this page are derived from 10,000 data-driven simulations of the Dolphins vs. Colts matchup, and they are correct at the time of publishing. They aim to assist you make better decisions when placing bets at online sportsbooks<\/a>.<\/p>\n Please note that when engaging in online betting, it is important to exercise responsible gambling practices and seek reputable sources for accurate and up-to-date information.<\/p>\n If you or a loved one has questions or needs to talk to a professional about gambling, call 1-800-GAMBLER or visit 1800gambler.net<\/a> for more information.<\/p>\n If you purchase a product or register for an account through a link on our site, we may receive compensation. By using this site, you consent to our User Agreement<\/a> and agree that your clicks, interactions, and personal information may be collected, recorded, and\/or stored by us and social media and other third-party partners in accordance with our Privacy Policy.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"The Indianapolis Colts open their 2025 season at home against the Miami Dolphins on Sunday, with plenty of…\n","protected":false},"author":2,"featured_media":347521,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2059],"tags":[2005,7,2004,392,2381,5648,6,3846],"class_list":{"0":"post-347520","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-indianapolis-colts","8":"tag-colts","9":"tag-football","10":"tag-indianapolis","11":"tag-indianapolis-colts","12":"tag-indianapoliscolts","13":"tag-isolated","14":"tag-nfl","15":"tag-nflraw24"},"share_on_mastodon":{"url":"https:\/\/channels.im\/@nfl\/115159935549603122","error":""},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/347520","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/comments?post=347520"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/347520\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media\/347521"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media?parent=347520"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/categories?post=347520"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/tags?post=347520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}