{"id":379777,"date":"2025-09-19T08:09:12","date_gmt":"2025-09-19T08:09:12","guid":{"rendered":"https:\/\/www.rawchili.com\/nfl\/379777\/"},"modified":"2025-09-19T08:09:12","modified_gmt":"2025-09-19T08:09:12","slug":"colts-vs-titans-spread-line-over-under","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/nfl\/379777\/","title":{"rendered":"Colts vs. Titans spread, line, over\/under"},"content":{"rendered":"

The Indianapolis Colts<\/a> (2-0) visit the Tennessee Titans<\/a> (0-2) on Sunday, September 21, 2025 in matchup between AFC South opponents at Nissan Stadium. Tennessee is a 3.5-point underdog.<\/p>\n

Colts vs. Titans game infoGame day: Sunday, September 21, 2025Game time: 1 p.m. ETTV channel: CBSLocation: Nashville, TennesseeStadium: Nissan StadiumLive stream: Watch this game on Fubo<\/a> (Regional restrictions may apply)Live stream: Watch this game on Paramount+<\/a> (Regional restrictions may apply)<\/p>\n

Watch Indianapolis Colts vs. Tennessee Titans on Fubo! (Regional restrictions may apply)<\/a><\/p>\n

Colts vs. Titans odds & betting linesSpread favorite: Indianapolis (-3.5)Moneyline: Indianapolis (-206), Tennessee (+169)Total: 43.5 points<\/p>\n

NFL odds courtesy of BetMGM Sportsbook<\/a>. Odds updated Thursday at 10:55 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub<\/a>.<\/p>\n

Colts vs. Titans recent matchupsIndianapolis has gone 4-1 versus Tennessee over the last five matchups between the two teams.The Colts and Titans haven’t gone over the total in any of their past five matchups, but Indianapolis is 4-1 against the spread in those games.Indianapolis has had the scoring advantage in those five matchups, totaling 122 points against Tennessee’s 110.Colts vs. Titans betting insightsIndianapolis, in two games with a spread this season, has not lost (2-0-0) against the spread. In one game as a moneyline favorite, the Colts won. Tennessee has won once against the spread so far this season (1-1-0). This is the third game this year the Titans are the moneyline underdog. They lost both of the games.Colts scoring insightsOn offense, the Colts have been making things happen over the previous three contests, putting up 31.0 points per game (fourth-best). They rank 11th over the last three games on defense (18.0 points per game allowed).Titans scoring insightsIn their past three games, the Titans are scoring 15.5 points per game (third-worst in NFL) and conceding 26.5 per game (23rd).Colts injury reportColts:
\nTyler Warren: Limited Participation in Practice (Toe),
\nCharvarius Ward: Full Participation in Practice (Concussion),
\nGrover Stewart: Did Not Participate In Practice (NIR – Rest),
\nBernhard Raimann: Limited Participation in Practice (Illness),
\nLaiatu Latu: Full Participation in Practice (Hamstring),
\nTyler Goodson: Full Participation in Practice (Elbow),
\nJosh Downs: Full Participation in Practice (Ankle),
\nAustin Ajiake: Full Participation in Practice (Throat),
\nJoe Bachie: Did Not Participate In Practice (Quadricep)Titans injury reportTitans:
\nKevin Zeitler: Limited Participation in Practice (Biceps),
\nKevin Winston Jr.: Limited Participation in Practice (Hamstring),
\nT’Vondre Sweat: Limited Participation in Practice (Ankle),
\nL’Jarius Sneed: Did Not Participate In Practice (Back),
\nBryce Oliver: Did Not Participate In Practice (Knee),
\nKalel Mullings: Limited Participation in Practice (Ankle),
\nJC Latham: Did Not Participate In Practice (Hip),
\nJarvis Brownlee: Limited Participation in Practice (Ankle)<\/p>\n

Watch Indianapolis Colts vs. Tennessee Titans on Fubo! (Regional restrictions may apply)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"The Indianapolis Colts (2-0) visit the Tennessee Titans (0-2) on Sunday, September 21, 2025 in matchup between AFC…\n","protected":false},"author":2,"featured_media":379778,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2061],"tags":[115,1466,821,247,265,357,5275,1107,861,874,2005,868,867,877,321,862,1109,864,3203,876,12716,7,1134,866,20842,723,2004,392,3198,248,267,246,88,6,35196,869,245,264,3197,818,865,2764,327,817,829,9,5433,1115,266,819,526,394,2411,3199,527,776,1108],"class_list":{"0":"post-379777","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-tennessee-titans","8":"tag-afc","9":"tag-afc-south","10":"tag-affiliate","11":"tag-american","12":"tag-american-football","13":"tag-and","14":"tag-autopilot","15":"tag-betting","16":"tag-cbs","17":"tag-cbs-corp","18":"tag-colts","19":"tag-commerce","20":"tag-contains","21":"tag-contains-commerce-or-affiliate-content","22":"tag-content","23":"tag-corp","24":"tag-disclaimer","25":"tag-exclude","26":"tag-exclude-from-paywall-logic-testing","27":"tag-exclude-smart-fronts","28":"tag-exclude-social-autopilot","29":"tag-football","30":"tag-from","31":"tag-fronts","32":"tag-hub","33":"tag-in","34":"tag-indianapolis","35":"tag-indianapolis-colts","36":"tag-logic","37":"tag-national","38":"tag-national-sports","39":"tag-neutral","40":"tag-news","41":"tag-nfl","42":"tag-nfl-hub","43":"tag-or","44":"tag-overall","45":"tag-overall-neutral","46":"tag-paywall","47":"tag-scores","48":"tag-smart","49":"tag-social","50":"tag-south","51":"tag-sport","52":"tag-sport-scores-u0026-statistics","53":"tag-sports","54":"tag-sports-betting","55":"tag-sports-betting-widget-and-disclaimer","56":"tag-sports-news","57":"tag-statistics","58":"tag-tennessee","59":"tag-tennessee-titans","60":"tag-tennesseetitans","61":"tag-testing","62":"tag-titans","63":"tag-u0026","64":"tag-widget"},"share_on_mastodon":{"url":"","error":"Validation failed: Text character limit of 500 exceeded"},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/379777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/comments?post=379777"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/379777\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media\/379778"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media?parent=379777"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/categories?post=379777"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/tags?post=379777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}