{"id":409892,"date":"2025-09-30T21:50:14","date_gmt":"2025-09-30T21:50:14","guid":{"rendered":"https:\/\/www.rawchili.com\/nfl\/409892\/"},"modified":"2025-09-30T21:50:14","modified_gmt":"2025-09-30T21:50:14","slug":"nfl-week-5-predictions-odds-for-every-matchup","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/nfl\/409892\/","title":{"rendered":"NFL Week 5 predictions, odds for every matchup"},"content":{"rendered":"<p><img decoding=\"async\" style=\"position:absolute;top:0;left:0;right:0;bottom:0;width:100%;height:100%;z-index:2\" src=\"https:\/\/www.rawchili.com\/nfl\/wp-content\/uploads\/2025\/09\/86408400007-jaxson-dart-092825.jpg\"\/><img decoding=\"async\" class=\"vidplayicon\" src=\"https:\/\/www.gannett-cdn.com\/appservices\/universal-web\/universal\/icons\/icon-play-alt-white.svg\" alt=\"play\" style=\"height:40px;margin:auto 18px auto 27px;width:40px\"\/><\/p>\n<p>NFL Week 4 Overreactions: Micah gets revenge, Dart lights it up<\/p>\n<p>USA TODAY Sports&#8217; Lorenzo Reyes &#8216;overreacts&#8217; to some of the best games from Sunday&#8217;s Week 4 slate.<\/p>\n<p>Sports Seriously<\/p>\n<p>The opening month of <a href=\"https:\/\/www.usatoday.com\/sports\/nfl?gnt-ste=usatoday\" rel=\"nofollow noopener\" target=\"_blank\">the 2025 NFL season<\/a> is in the books and the first slate of October games arrives with just two undefeated teams heading into Week 5. They also happen to be two of the <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/2025\/08\/31\/super-bowl-odds-ravens-bills-eagles-week-1\/85858320007\/\" rel=\"nofollow noopener\" target=\"_blank\">preseason Super Bowl favorites<\/a>.<\/p>\n<p>The <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/philadelphia-eagles\/354\/stats\" rel=\"nofollow noopener\" target=\"_blank\">Philadelphia Eagles<\/a> (4-0) and <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/buffalo-bills\/324\/stats\" rel=\"nofollow noopener\" target=\"_blank\">Buffalo Bills<\/a> (4-0) will be challenged on Sunday if some of the early picks and predictions are to be believed. Though both teams are favorites, the Eagles (hosting the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/denver-broncos\/332\/stats\" rel=\"nofollow noopener\" target=\"_blank\">Denver Broncos<\/a>) and the Bills (hosting the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/new-england-patriots\/348\/\" rel=\"nofollow noopener\" target=\"_blank\">New England Patriots<\/a>) could be in dangerous spots. The first bye weeks of the year are also here, which means there are fewer matchups on <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/schedule?week=5\" rel=\"nofollow noopener\" target=\"_blank\">the schedule around the country<\/a>. But there remain plenty of fun storylines with teams jockeying for position as separation starts to develop in the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/standings\" rel=\"nofollow noopener\" target=\"_blank\">NFL standings<\/a>.<\/p>\n<p>The intrigue begins with &#8220;Thursday Night Football&#8221; in Week 5 as the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/san-francisco-49ers\/359\/\" rel=\"nofollow noopener\" target=\"_blank\">San Francisco 49ers<\/a> and <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/los-angeles-rams\/343\/\" rel=\"nofollow noopener\" target=\"_blank\">Los Angeles Rams<\/a> put 3-1 records on the line in an NFC West tilt. Sunday features the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/seattle-seahawks\/361\/\" rel=\"nofollow noopener\" target=\"_blank\">Seattle Seahawks<\/a> (3-1) hosting the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/tampa-bay-buccaneers\/362\/\" rel=\"nofollow noopener\" target=\"_blank\">Tampa Bay Buccaneers<\/a> (3-1) in another matchup of NFC contenders. There&#8217;s also a crucial game between the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/baltimore-ravens\/366\/\" rel=\"nofollow noopener\" target=\"_blank\">Baltimore Ravens<\/a> and <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/houston-texans\/325\/\" rel=\"nofollow noopener\" target=\"_blank\">Houston Texans<\/a> with both teams off to 1-3 starts.<\/p>\n<p>The <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/los-angeles-chargers\/357\/\" rel=\"nofollow noopener\" target=\"_blank\">Los Angeles Chargers<\/a> (3-1) vs. <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/washington-commanders\/363\/\" rel=\"nofollow noopener\" target=\"_blank\">Washington Commanders<\/a> (2-2), perhaps with a returning <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/players\/jayden-daniels\/1161228\" rel=\"nofollow noopener\" target=\"_blank\">Jayden Daniels<\/a>, also highlights the late afternoon kickoffs on Sunday, while the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/kansas-city-chiefs\/339\/\" rel=\"nofollow noopener\" target=\"_blank\">Kansas City Chiefs<\/a> (2-2) face the <a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/jacksonville-jaguars\/365\/\" rel=\"nofollow noopener\" target=\"_blank\">Jacksonville Jaguars<\/a> (3-1) on the road in a &#8220;Monday Night Football&#8221; matchup featuring two AFC contenders to wrap up the Week 5 action.<\/p>\n<p>Here is an early look at picks, predictions and odds for all of the\u00a0Week 5 games on the 2025 NFL schedule:<\/p>\n<p>NFL Week 5 game predictions, picks<\/p>\n<p>Odds courtesy of\u00a0<a href=\"https:\/\/www.usatoday.com\/online-betting\/sports\/betmgm\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">BetMGM<\/a>\u00a0as of Tuesday, Sept. 30 at 2 p.m. ET.<\/p>\n<p>Date: Thursday, Oct. 2Time: 8:15 p.m. ETLocation: SoFi Stadium (Inglewood, California)TV: NoneStreaming:\u00a0<a href=\"https:\/\/www.amazon.com\/salp\/tnf?tag=smglocal-20\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Amazon Prime<\/a>, NFL+Spread: Rams (-6)<a href=\"https:\/\/www.cbssports.com\/nfl\/news\/nfl-week-5-picks-score-predictions-rams-edge-49ers-seahawks-top-buccaneers\/\" rel=\"nofollow noopener\" target=\"_blank\">CBS Sports<\/a>: Rams 24, 49ers 17<\/p>\n<p>&#8220;The 49ers are banged up, and now, they have to play a road game on a short week against a division rival that has beaten them three straight times. Also, the 49ers are going to be starting a banged-up QB and that&#8217;s exactly what you don&#8217;t want to do when you&#8217;re about to face a Rams defense that&#8217;s tied for the second-most sacks in the NFL this year. The Rams defense is going to feast.&#8221;<\/p>\n<p><a href=\"https:\/\/www.azcentral.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-5-picks-predictions-scores-2025-season\/84061970007\/\" rel=\"nofollow noopener\" target=\"_blank\">Arizona Republic<\/a>: Rams 27, 49ers 24<\/p>\n<p>&#8220;The winner of this games moves to 4-1 and gets an early edge in the NFC West race. The Rams&#8217; defense will make a big play late to give Matthew Stafford and company a big win at home.&#8221;<\/p>\n<p>Date: Sunday, Oct. 5Time: 9:30 a.m. ETLocation: Tottenham Hotspur Stadium (London)TV: NFL NetworkStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL+Spread: Vikings (-3.5)<a href=\"https:\/\/www.sportingnews.com\/us\/nfl\/news\/nfl-picks-predictions-week-5\/984f024c3192a11d1861216c\" rel=\"nofollow noopener\" target=\"_blank\">Sporting News<\/a>: Vikings 20, Browns 14<\/p>\n<p>&#8220;The Vikings&#8217; overseas tour continues in London. Cleveland&#8217;s offensive struggles continue, and quarterback Joe Flacco has two TDs and four interceptions. Will Dillon Gabriel get a shot? Minnesota will make due with Carson Wentz if he starts in place of J.J. McCarthy.&#8221;<\/p>\n<p><a href=\"https:\/\/www.cbssports.com\/nfl\/news\/nfl-week-5-picks-score-predictions-rams-edge-49ers-seahawks-top-buccaneers\/\" rel=\"nofollow noopener\" target=\"_blank\">CBS Sports<\/a>: Browns 19, Vikings 16<\/p>\n<p>&#8220;No idea who Cleveland&#8217;s starting QB is going to be on Sunday, but no matter who it is &#8230; the Vikings have surrendered the eighth-most rushing yards in the NFL this year and the Browns need to do everything they can to take advantage of that.\u00a0In two starts, (Carson) Wentz is averaging 261.5 passing yards per game, but he&#8217;s also been sacked NINE TIMES. And now, he has to face the best defense in the NFL.&#8221;<\/p>\n<p><a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"sponsored noreferrer noopener nofollow\">Watch NFL Week 5 games with Fubo<\/a><\/p>\n<p>Date: Sunday, Oct. 5Time: 1 p.m. ETLocation: M&amp;T Bank Stadium (Baltimore)TV: CBSStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Texans (-2.5)<a href=\"https:\/\/www.azcentral.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-5-picks-predictions-scores-2025-season\/84061970007\/\" rel=\"nofollow noopener\" target=\"_blank\">Arizona Republic<\/a>: Ravens 23, Texans 20<\/p>\n<p>&#8220;Did anyone think both the Texans and Ravens would be 1-3 at this point of the season when the NFL schedule came out? Hard to believe that one of them could fall to 1-4 on the season.&#8221;<\/p>\n<p><a href=\"https:\/\/www.si.com\/betting\/road-to-272-bets-nfl-week-5-picks-for-every-game-01k6b76ppgnb\" rel=\"nofollow noopener\" target=\"_blank\">Sports Illustrated<\/a>: Back the Texans<\/p>\n<p>&#8220;The side to back is the Texans with the points in this spot, especially with Lamar Jackson dealing with a hamstring injury. The Houston offense has struggled this season, but so has the Baltimore defense.&#8221;<\/p>\n<p>Date: Sunday, Oct. 5Time: 1 p.m. ETLocation: Bank of America Stadium (Charlotte, North Carolina)TV: FOXStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Dolphins (-1.5)<\/p>\n<p class=\"related-link\">TYREEK HILL INJURY FALLOUT: <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/dolphins\/2025\/09\/30\/tyreek-hill-injury-miami-dolphins-mike-mcdaniel-chris-grier\/86437356007\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Dolphins with no easy outs to repair mess of their own making<\/a><\/p>\n<p><a href=\"https:\/\/www.sportingnews.com\/us\/nfl\/news\/nfl-picks-predictions-week-5\/984f024c3192a11d1861216c\" rel=\"nofollow noopener\" target=\"_blank\">Sporting News<\/a>: Dolphins 26, Panthers 23<\/p>\n<p>&#8220;The Panthers won their only other home game, 30-0, which makes this a tough line to gauge. Miami coach Mike McDaniel remains on the hot seat \u2013 and the Dolphins are on a short week. The Dolphins were a 2-0 against the spread as a road favorite last season.&#8221;\u00a0<\/p>\n<p><a href=\"https:\/\/www.azcentral.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-5-picks-predictions-scores-2025-season\/84061970007\/\" rel=\"nofollow noopener\" target=\"_blank\">Arizona Republic<\/a>: Panthers 24, Dolphins 23<\/p>\n<p>&#8220;The Panthers are 0-3 on the road this season and 1-0 at home. This game is in Carolina. We&#8217;ll take Bryce Young and company at home, but just barely.&#8221;<\/p>\n<p>Date: Sunday, Oct. 5Time: 1 p.m. ETLocation: Caesars Superdome (New Orleans)TV: CBSStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Saints (-2)<a href=\"https:\/\/nypost.com\/2025\/09\/29\/betting\/nfl-week-5-early-predictions-best-bets-picks-to-target-before-lines-move\/\" rel=\"nofollow noopener\" target=\"_blank\">New York Post<\/a>: Pick the Giants<\/p>\n<p>&#8220;No one feels bad for Big Blue that they lost Malik Nabers to an ACL injury. And let\u2019s also just call the loss of a receiver due to this injury, and an ensuing line move of two points, overly dramatic. Sure, Nabers was the biggest part of their offense. However, the Giants have just injected a new quarterback who defeated one of the Super Bowl favorites. &#8230; This is a nightmare matchup for the Saints, who are 27th in pass block win rate and 31st in run block win rate.&#8221;<\/p>\n<p><a href=\"https:\/\/www.azcentral.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-5-picks-predictions-scores-2025-season\/84061970007\/\" rel=\"nofollow noopener\" target=\"_blank\">Arizona Republic<\/a>: Giants 28, Saints 20<\/p>\n<p>&#8220;The\u00a0<a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/new-york-giants\/351\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">New York Giants<\/a>\u00a0have hope with Jaxson Dart after a big win over the Los Angeles Chargers. The\u00a0<a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/new-orleans-saints\/350\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Saints<\/a>? They will remain the NFC&#8217;s only winless team.&#8221;<\/p>\n<p class=\"related-link\">WHAT WE LEARNED NFL WEEK 4: <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/columnist\/nate-davis\/2025\/09\/28\/nfl-week-4-takeaways-chiefs-giants-jaxson-dart-malik-nabers\/86409007007\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Giants, Jaxson Dart win (with collateral damage)<\/a><\/p>\n<p>Date: Sunday, Oct. 5Time: 1 p.m. ETLocation: Lucas Oil Stadium (Indianapolis)TV: FOXStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Colts (-7)<a href=\"https:\/\/www.sportingnews.com\/us\/nfl\/news\/nfl-picks-predictions-week-5\/984f024c3192a11d1861216c\" rel=\"nofollow noopener\" target=\"_blank\">Sporting News<\/a>: Colts 28, Raiders 21<\/p>\n<p>&#8220;The Raiders are improving with Pete Carroll, and Ashton Jeanty is coming off a 138-yard performance against the Bears. On the other side, Jonathan Taylor continues to lead the NFL with 414 rushing yards. The Colts and Raiders are both good against the run, so quarterbacks Geno Smith and Daniel Jones will have to make plays. Who does that without turnovers?&#8221;<\/p>\n<p><a href=\"https:\/\/www.si.com\/betting\/road-to-272-bets-nfl-week-5-picks-for-every-game-01k6b76ppgnb\" rel=\"nofollow noopener\" target=\"_blank\">Sports Illustrated<\/a>: Raiders cover<\/p>\n<p>&#8220;The Las Vegas Raiders are certainly not a playoff team, but aren&#8217;t as bad as the betting market is treating them. &#8230; The Colts&#8217; offense has been fantastic this season, but they showed last week that they have a turnover issue, and Daniel Jones had moments where he looked like the quarterback of old, including a game-sealing interception.&#8221;<\/p>\n<p>Date: Sunday, Oct. 5Time: 1 p.m. ETLocation: MetLife Stadium (East Rutherford, New Jersey)TV: FOXStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Cowboys (-2.5)<a href=\"https:\/\/www.azcentral.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-5-picks-predictions-scores-2025-season\/84061970007\/\" rel=\"nofollow noopener\" target=\"_blank\">Arizona Republic<\/a>: Cowboys 31, Jets 20<\/p>\n<p>&#8220;The Cowboys are coming off a rare tie to the Green Bay Packers, 40-40. While Dallas has had its struggles, it has put points on the board this season. New York won&#8217;t be able to keep up.&#8221;<\/p>\n<p><a href=\"https:\/\/www.sportingnews.com\/us\/nfl\/news\/nfl-picks-predictions-week-5\/984f024c3192a11d1861216c\" rel=\"nofollow noopener\" target=\"_blank\">Sporting News<\/a>: Cowboys 31, Jets 24<\/p>\n<p>&#8220;How will the Cowboys use the momentum from the 40-40 tie against the Packers in Week 4? George Pickens is coming off his best game \u2013 but the defense continues to give up a league-worst 420.5 yards per game. The Jets are coming off a short week, and they&#8217;ll need to generate a few turnovers. Look for the Cowboys to feed Javonte Williams against a shaky Jets run defense.&#8221;<\/p>\n<p class=\"related-link\">NFL WEEK 4 WINNERS AND LOSERS: <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-4-winners-losers-packers-cowboys-tie-injuries\/86406868007\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Packers&#8217; tie with Cowboys feels like a loss<\/a><\/p>\n<p>Date: Sunday, Oct. 5Time: 1 p.m. ETLocation: Lincoln Financial Field (Philadelphia)TV: CBSStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Eagles (-3.5)<a href=\"https:\/\/www.si.com\/betting\/road-to-272-bets-nfl-week-5-picks-for-every-game-01k6b76ppgnb\" rel=\"nofollow noopener\" target=\"_blank\">Sports Illustrated<\/a>: Broncos get an upset<\/p>\n<p>&#8220;The Philadelphia Eagles may be 4-0, but there are a lot of signs that should concern Eagles fans. &#8230; Not only do their underlying numbers not match their record, but now they have to take on one of the best defenses in the NFL in the Denver Broncos. &#8230; If the defense can stand tall, the Broncos are going to be live to hand the Eagles their first loss of the season.&#8221;<\/p>\n<p><a href=\"https:\/\/www.azcentral.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-5-picks-predictions-scores-2025-season\/84061970007\/\" rel=\"nofollow noopener\" target=\"_blank\">Arizona Republic<\/a>: Eagles 27, Broncos 19<\/p>\n<p>&#8220;The\u00a0<a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/denver-broncos\/332\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Broncos<\/a>\u00a0get to go east on a short week against an\u00a0<a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/teams\/philadelphia-eagles\/354\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Eagles<\/a>\u00a0team that just finds ways to win at home. That&#8217;s not good news for Denver.&#8221;<\/p>\n<p>Date: Sunday, Oct. 5Time: 4:05 p.m. ETLocation: Lumen Field (Seattle)TV: CBSStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Seahawks (-3.5)<a href=\"https:\/\/www.cbssports.com\/nfl\/news\/nfl-week-5-picks-score-predictions-rams-edge-49ers-seahawks-top-buccaneers\/\" rel=\"nofollow noopener\" target=\"_blank\">CBS Sports<\/a>: Seahawks 23, Buccaneers 20<\/p>\n<p>&#8220;The Bucs will be facing one of the best pass defenses that they&#8217;ve seen this year. Only four teams have held opposing quarterbacks to a QB rating of 76 or less and the\u00a0<a href=\"https:\/\/www.cbssports.com\/nfl\/teams\/SEA\/seattle-seahawks\/\" rel=\"nofollow noopener\" target=\"_blank\">Seahawks<\/a>\u00a0are one of them. Only six teams have recorded 12 or more sacks this year and the Seahawks are one of them. Only three teams have seven or more interceptions this year, and yup, the Seahawks are one of them.\u00a0The Bucs haven&#8217;t won in Seattle since 2009.&#8221;<\/p>\n<p><a href=\"https:\/\/www.sportingnews.com\/us\/nfl\/news\/nfl-picks-predictions-week-5\/984f024c3192a11d1861216c\" rel=\"nofollow noopener\" target=\"_blank\">Sporting News<\/a>: Buccaneers 28, Seahawks 27<\/p>\n<p>&#8220;The Buccaneers&#8217; tough early-season schedule continues against the Seahawks, who have a little extra rest after their Thursday Night Football victory at Arizona. Both teams excel at stopping the run, and the Seahawks have generated a few more turnovers. Baker Mayfield, however, has just one interception this season. It&#8217;s another dramatic finish with Sam Darnold in a battle between the No. 1 and No. 3 picks in the 2018 NFL Draft.&#8221;\u00a0<\/p>\n<p>Date: Sunday, Oct. 5Time: 4:05 p.m. ETLocation: State Farm Stadium (Glendale, Arizona)TV: CBSStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Cardinals (-8.5)<a href=\"https:\/\/www.azcentral.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-5-picks-predictions-scores-2025-season\/84061970007\/\" rel=\"nofollow noopener\" target=\"_blank\">Arizona Republic<\/a>: Cardinals 24, Titans 13<\/p>\n<p>&#8220;The Titans have only scored 51 points in four games. The Cardinals have lost two straight games on last-second field goals. This game won&#8217;t come down to that.&#8221;<\/p>\n<p><a href=\"https:\/\/www.si.com\/betting\/road-to-272-bets-nfl-week-5-picks-for-every-game-01k6b76ppgnb\" rel=\"nofollow noopener\" target=\"_blank\">Sports Illustrated<\/a>: Bet Titans to cover big spread<\/p>\n<p>&#8220;As bad as (the Titans) are, &#8230; the Cardinals rank 22nd in the NFL in Net Yards per Play (-0.6). They also rank 26th in offensive success rate. This is the ultimate buy-low spot on the Titans.&#8221;<\/p>\n<p class=\"related-link\">NFL POWER RANKINGS WEEK 5: <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/columnist\/nate-davis\/2025\/09\/30\/nfl-power-rankings-week-5-winless-jets-saints-titans\/86433582007\/\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">Who&#8217;s at bottom as Jets join 0-4 squads?<\/a><\/p>\n<p>Date: Sunday, Oct. 5Time: 4:25 p.m. ETLocation: Paycor Stadium (Cincinnati)TV: FOXStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Lions (-10)<a href=\"https:\/\/www.cbssports.com\/nfl\/news\/nfl-week-5-best-bets-expert-advises-whether-you-should-jump-on-these-nfl-picks-now-or-later\/\" rel=\"nofollow noopener\" target=\"_blank\">CBS Sports<\/a>: Bet the Lions<\/p>\n<p>&#8220;The Lions were just favored at home by 10 against the\u00a0Browns\u00a0\u2012 a team with an actually good defense and an equally comparable offense to the\u00a0Bengals\u00a0\u2012 and it didn&#8217;t stop anyone from betting on them or the Lions from covering pretty easily.&#8221;<\/p>\n<p><a href=\"https:\/\/www.sportingnews.com\/us\/nfl\/news\/nfl-picks-predictions-week-5\/984f024c3192a11d1861216c\" rel=\"nofollow noopener\" target=\"_blank\">Sporting News<\/a>: Lions 31, Bengals 20<\/p>\n<p>&#8220;The\u00a0Lions\u00a0have found their offensive stride with Jared Goff \u2013 who has a 77.95 completion percentage in three games since the Week 1 loss at Green Bay. The Bengals are 0-2 against the spread as a home underdog the last three seasons \u2013 so it&#8217;s a rare occasion to rise up in this situation. Detroit is 11-2 against the spread as a road favorite since 2023.&#8221;<\/p>\n<p>Date: Sunday, Oct. 5Time: 4:25 p.m. ETLocation: SoFi Stadium (Inglewood, California)TV: FOXStreaming:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, NFL Sunday TicketSpread: Chargers (-2.5)<a href=\"https:\/\/sports.betmgm.com\/en\/blog\/nfl\/expert-picks-week-5-this-season-bm16\/\" rel=\"nofollow noopener\" target=\"_blank\">BetMGM<\/a>: Pick the Commanders<\/p>\n<p>&#8220;Joe Alt left Sunday\u2019s game against the Giants with an ankle injury. That further decimates an already banged-up Chargers offensive line.\u00a0If Alt and Mekhi Becton miss Sunday\u2019s game, the Chargers\u2019 offensive prowess likely shrinks.\u00a0Conversely, Washington\u2019s offense looked decent in Atlanta without arguably its two best players. &#8230; Jayden Daniels\u2019 return also provides a matchup advantage for the Commanders offense.&#8221;<\/p>\n<p><a href=\"https:\/\/sports.yahoo.com\/nfl\/betting\/article\/early-week-5-nfl-bets-to-make-right-now-back-the-commanders-141054895.html\" rel=\"nofollow noopener\" target=\"_blank\">Yahoo Sports<\/a>: Commanders cover<\/p>\n<p>&#8220;Expect the Commanders to get Jayden Daniels back for this game. &#8230; Injuries to the offensive line are going to disrupt QB Justin Herbert\u2019s time to evaluate his options down the field and will force the Chargers to change the game plan that has gotten them off to a 3-1 start this season.&#8221;<\/p>\n<p><a href=\"https:\/\/imp.i305175.net\/anPaeY\" target=\"_blank\" rel=\"sponsored noreferrer noopener nofollow\">Watch Bills vs. Patriots with Peacock<\/a><\/p>\n<p>Date: Sunday, Oct. 5Time: 8:20 p.m. ETLocation: Highmark Stadium (Orchard Park, New York)TV: NBCStreaming:\u00a0<a href=\"https:\/\/imp.i305175.net\/anPaeY\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Peacock<\/a>,\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>Spread: Bills (-7.5)<a href=\"https:\/\/www.azcentral.com\/story\/sports\/nfl\/2025\/09\/29\/nfl-week-5-picks-predictions-scores-2025-season\/84061970007\/\" rel=\"nofollow noopener\" target=\"_blank\">Arizona Republic<\/a>: Bills 34, Patriots 20<\/p>\n<p>&#8220;Can the Patriots upset the Bills on Sunday Night Football? It could happen. We just don&#8217;t think Drake Maye and New England&#8217;s offense can keep up with Josh Allen and Buffalo on the road.&#8221;<\/p>\n<p><a href=\"https:\/\/www.si.com\/betting\/road-to-272-bets-nfl-week-5-picks-for-every-game-01k6b76ppgnb\" rel=\"nofollow noopener\" target=\"_blank\">Sports Illustrated<\/a>: Bet Patriots to pull off an upset<\/p>\n<p>&#8220;Drake Maye has had a fantastic start to his sophomore season. &#8230; This has all the makings of an offensive shootout, and if the Bills aren&#8217;t careful, the Patriots have a chance of pulling off an AFC East upset.&#8221;<\/p>\n<p><a href=\"https:\/\/sling-tv.pxf.io\/55kbn2\" target=\"_blank\" rel=\"sponsored noreferrer noopener nofollow\">Watch Monday Night Football with Sling TV<\/a><\/p>\n<p>Date: Monday, Oct. 6Time: 8:15 p.m. ETLocation: Everbank Stadium (Jacksonville, Florida)TV: ABC, ESPN, ESPN2 (Manningcast)Streaming:\u00a0<a href=\"https:\/\/go.web.plus.espn.com\/c\/1205322\/531511\/9070?u=https%3A%2F%2Fplus.espn.com%2F&amp;subId1=USAT2025\" rel=\"nofollow noopener\" target=\"_blank\">ESPN Unlimited<\/a>, <a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=1205322&amp;subId1=USAT&amp;subId2=NFL&amp;subId3=2025\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Fubo<\/a>, <a href=\"https:\/\/sling-tv.pxf.io\/55kbn2\" rel=\"nofollow noopener\" target=\"_blank\">Sling TV<\/a>Spread: Chiefs (-3.5)<a href=\"https:\/\/www.cbssports.com\/nfl\/news\/nfl-week-5-picks-score-predictions-rams-edge-49ers-seahawks-top-buccaneers\/\" rel=\"nofollow noopener\" target=\"_blank\">CBS Sports<\/a>: Chiefs 27, Jaguars 23<\/p>\n<p>&#8220;The Jags are averaging 144 yards per game on the ground, which is the third-highest total in the NFL. Most of that total has come from\u00a0<a href=\"https:\/\/www.cbssports.com\/nfl\/players\/2809206\/travis-etienne\/\" rel=\"nofollow noopener\" target=\"_blank\">Travis Etienne<\/a> &#8230; so if they can get Etienne going, that could be the secret to pulling off an upset here.\u00a0&#8230; Kansas City is coming off a win over Baltimore in Week 4 and will be facing the\u00a0<a href=\"https:\/\/www.cbssports.com\/nfl\/teams\/DET\/detroit-lions\/\" rel=\"nofollow noopener\" target=\"_blank\">Lions<\/a>\u00a0in Week 6. &#8230; The return of\u00a0<a href=\"https:\/\/www.cbssports.com\/nfl\/players\/26730787\/xavier-worthy\/\" rel=\"nofollow noopener\" target=\"_blank\">Xavier Worthy<\/a>\u00a0last week sparked a Chiefs offense that desperately needed a spark.&#8221;<\/p>\n<p><a href=\"https:\/\/www.nytimes.com\/athletic\/6676467\/2025\/09\/30\/nfl-best-bets-week-5-dart-nix\/\" rel=\"nofollow noopener\" target=\"_blank\">The Athletic<\/a>: Jaguars cover<\/p>\n<p>&#8220;Yes, Xavier Worthy was back last week, and (the Chiefs) lit up the Ravens, but the offensive explosion had more to do with the Ravens losing just about every defensive starter throughout the course of the game. &#8230; It\u2019s taken a bit, but Liam Coen and Trevor Lawrence are starting to jell and should only improve if Brian Thomas Jr. can get back on track.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"NFL Week 4 Overreactions: Micah gets revenge, Dart lights it up USA TODAY Sports&#8217; Lorenzo Reyes &#8216;overreacts&#8217; to&hellip;\n","protected":false},"author":2,"featured_media":409893,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[821,247,265,357,1107,868,867,877,321,1109,7,20842,677,679,248,267,330,88,6,35196,907,869,245,338,529,818,817,829,9,5433,1115,266,819,678,24,528,536,776,1108],"class_list":{"0":"post-409892","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nfl","8":"tag-affiliate","9":"tag-american","10":"tag-american-football","11":"tag-and","12":"tag-betting","13":"tag-commerce","14":"tag-contains","15":"tag-contains-commerce-or-affiliate-content","16":"tag-content","17":"tag-disclaimer","18":"tag-football","19":"tag-hub","20":"tag-modular","21":"tag-modular-story","22":"tag-national","23":"tag-national-sports","24":"tag-negative","25":"tag-news","26":"tag-nfl","27":"tag-nfl-hub","28":"tag-now","29":"tag-or","30":"tag-overall","31":"tag-overall-negative","32":"tag-point","33":"tag-scores","34":"tag-sport","35":"tag-sport-scores-u0026-statistics","36":"tag-sports","37":"tag-sports-betting","38":"tag-sports-betting-widget-and-disclaimer","39":"tag-sports-news","40":"tag-statistics","41":"tag-story","42":"tag-the","43":"tag-to","44":"tag-to-the-point","45":"tag-u0026","46":"tag-widget"},"share_on_mastodon":{"url":"","error":"Validation failed: Text character limit of 500 exceeded"},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/409892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/comments?post=409892"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/409892\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media\/409893"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media?parent=409892"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/categories?post=409892"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/tags?post=409892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}