{"id":645355,"date":"2026-01-01T10:45:47","date_gmt":"2026-01-01T10:45:47","guid":{"rendered":"https:\/\/www.rawchili.com\/nfl\/645355\/"},"modified":"2026-01-01T10:45:47","modified_gmt":"2026-01-01T10:45:47","slug":"computer-model-locks-in-jaguars-vs-colts-picks-score-prediction-2","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/nfl\/645355\/","title":{"rendered":"Computer model locks in Jaguars vs. Colts picks, score prediction"},"content":{"rendered":"<p>    <img decoding=\"async\" class=\"Article-featuredImageImg\" alt=\"trevor-lawrence-jacksonville-jaguars\" src=\"https:\/\/www.rawchili.com\/nfl\/wp-content\/uploads\/2026\/01\/trevor-lawrence-jags-imagn.jpg\" loading=\"lazy\" height=\"433\" width=\"770\"\/><\/p>\n<p>                Imagn Images<\/p>\n<p>AFC South rivals square off in Week 17 of the 2025 NFL season when the Jacksonville Jaguars visit the Indianapolis Colts. The Jaguars are in the mix for the No. 1 seed in the AFC, while the Colts are set to miss the playoffs despite starting the season 8-2, thanks in large part to Daniel Jones&#8217; season-ending injury. The Jaguars won the first meeting between these teams, 36-19.<\/p>\n<p>Kickoff from Lucas Oil Stadium is set for 1 p.m. ET. Jacksonville is a 5.5-point favorite in the latest Jaguars vs. Colts odds at <a href=\"https:\/\/www.cbssports.com\/betting\/news\/draftkings-promo-code\/\" target=\"_blank\" rel=\"nofollow noopener\">DraftKings<\/a>, and the total comes in at 48.5. The Jags are -257 money line favorites (risk $257 to win $100), while the Colts are +209 underdogs. Before making any Colts vs. Jaguars picks of your own, make sure to look at the top\u00a0<a href=\"https:\/\/cbssports.com\/nfl\/picks\/experts\/\" rel=\"nofollow noopener\" target=\"_blank\">NFL picks<\/a>\u00a0from the SportsLine Projection Model, which simulates every\u00a0<a href=\"https:\/\/cbssports.com\/nfl\/\" target=\"_blank\" rel=\"nofollow noopener\">NFL<\/a>\u00a0game 10,000 times.<\/p>\n<p>Where to watch Jaguars vs. Colts on Sunday<\/p>\n<p>When:\u00a0Sunday, Dec. 28<br \/>Time:\u00a01 p.m. ET<br \/>TV:\u00a0FOX<br \/>Stream:\u00a0<a href=\"https:\/\/www.fubo.tv\/welcome\/leagues\/191277?irad=356362&amp;irmp=365718\" target=\"_blank\" rel=\"nofollow noopener\">Fubo<\/a>\u00a0\u00a0<br \/>Follow along:\u00a0<a href=\"https:\/\/www.cbssports.com\/mobile\" target=\"_blank\" rel=\"nofollow noopener\">CBS Sports App<\/a><\/p>\n<p>Jaguars vs. Colts betting preview<\/p>\n<p>Odds: Jaguars -5.5, over\/under 48.5<\/p>\n<p>Jacksonville is thriving in Liam Coen&#8217;s first season and has gone 10-5 ATS on the season. The Colts are 7-6-2 ATS on the season but have faltered of late since a lot of their covers came early in the season when there was doubt over Jones&#8217; abilities. Indianapolis is 8-7 to the Over while Jacksonville is 9-6 to the Over.<\/p>\n<p>Jaguars vs. Colts SGPColts +5.5Over 48.5Jakobi Meyers anytime touchdown scorer<\/p>\n<p>Bet it at DraftKings:<\/p>\n<p>Model&#8217;s Jaguars vs. Colts score prediction, picks<\/p>\n<p>The SportsLine Projection Model has the Colts covering the 5.5-point spread in 55% of simulationsm and Indianapolis wins in 41% of simulations, offering value at +240 odds. The Over on 48.5 hits in 50% of simulations.<\/p>\n<p>Jaguars vs. Colts score prediction: Jaguars 27, Colts 23<\/p>\n<p>Want more Week 17 NFL picks?<\/p>\n<p>You&#8217;ve seen the model&#8217;s best bets for Jacksonville Jaguars vs. Indianapolis Colts. Now,\u00a0<a href=\"https:\/\/www.sportsline.com\/nfl\/\" target=\"_blank\" rel=\"nofollow noopener\">get against the spread, total and money-line picks for every Week 17 NFL game here<\/a>, all from the model that&#8217;s simulated every game 10,000 times.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"Imagn Images AFC South rivals square off in Week 17 of the 2025 NFL season when the Jacksonville&hellip;\n","protected":false},"author":2,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2060],"tags":[1107,85218,7,392,212,125,2401,213,86640,92926,92925,92927,92928,6,6020,35614,19664,50329,62431,92895,92896],"class_list":["post-645355","post","type-post","status-publish","format-standard","category-jacksonville-jaguars","tag-betting","tag-colts-channel","tag-football","tag-indianapolis-colts","tag-jacksonville","tag-jacksonville-jaguars","tag-jacksonvillejaguars","tag-jaguars","tag-jaguars-channel","tag-jaguars-colts-odds","tag-jaguars-colts-picks","tag-jaguars-colts-prediction","tag-jaguars-colts-props","tag-nfl","tag-nfl-betting","tag-nfl-odds","tag-nfl-picks","tag-nfl-props","tag-nfl-week-17","tag-week-17-odds","tag-week-17-props"],"share_on_mastodon":{"url":"https:\/\/channels.im\/@nfl\/115819445305355401","error":""},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/645355","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/comments?post=645355"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/posts\/645355\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/media?parent=645355"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/categories?post=645355"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/nfl\/wp-json\/wp\/v2\/tags?post=645355"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}