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Tage Thompson and Jimmy Snuggerud will be leading the charge for the Buffalo Sabres and St. Louis Blues, respectively, when the two teams play on Thursday, Nov. 6 at KeyBank Center, with the puck dropping at 7 p.m. ET. Take a look at everything you need to know about the Sabres-Blues game, from the puck lined, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Sabres vs. Blues Game Information and TV ChannelWhen: Thursday, November 6, 2025 at 7 p.m. ETWhere: KeyBank Center in Buffalo, New YorkTV: ESPN+Live Boxscore: FOX Sports Sabres vs Blues Betting Information Favorite Puck Line Favorite Puck Line Odds Underdog Puck Line Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline Sabres -1.5 190 -230 6.5 100 -120 -130 +110

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Sabres vs. Blues Prediction

ATS Pick: Sabres (- 1.5)
O/U Pick: Over (6.5)
Score Prediction: Sabres 5 – Blues 2

Sabres vs. Blues Betting InsightsBuffalo and its opponent have gone over 6.5 combined goals in six of 13 games this season.St. Louis’ games this season have had more than 6.5 goals eight of 14 times.These teams are scoring 5.6 goals per game between them, 0.9 fewer than this game’s total.These two teams surrender 7.2 goals per game combined, 0.7 more than the total for this game.The Sabres are 24th in goals scored in the league, and the Blues are 21st.The Sabres are 15th in the league in goals conceded, and the Blues are 32nd.Sabres StatsThe Sabres’ 37 total goals (2.8 per game) make them the 24th-ranked scoring team in the league.Buffalo has given up 40 total goals (3.1 per game), ranking 15th in league play in goals against.Their goal differential (-3) ranks 21st in the league.The eight power-play goals Buffalo has recorded this season (to rank 19th in the NHL) have come on 42 chances.The Sabres’ 19.05% power-play conversion rate ranks 19th in the league.The two shorthanded goals Buffalo has scored this season rank fifth among all NHL squads.Sabres Leaders Name Games Goals Assists Points Giveaways Takeaways Faceoff Win % Alex Tuch 13 4 7 11 9 3 30% Tage Thompson 13 5 5 10 13 9 51.2% Josh Doan 13 5 4 9 13 6 66.7% Rasmus Dahlin 13 1 8 9 30 6 – Zachary Benson 8 0 9 9 7 5 66.7% Blues StatsThe Blues have 38 goals this season (2.7 per game), 21st in the league.St. Louis’ total of 58 goals allowed (4.1 per game) ranks 32nd in the league.They have the 32nd-ranked goal differential in the league at -20.St. Louis has nine power-play goals (on 39 chances), 14th in the NHL.The Blues score on 23.08% of their power plays, No. 10 in the league.This season, St. Louis has one shorthanded goal (ninth in NHL).Blues Leaders

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