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At 7 p.m. ET on Friday, Nov. 21, Tage Thompson and Connor Bedard will go head-to-head in a matchup between the Buffalo Sabres and Chicago Blackhawks at KeyBank Center. Check out everything you need to know to know about the Sabres-Blackhawks game, from the puck lined, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Sabres vs. Blackhawks Game Information and TV ChannelWhen: Friday, November 21, 2025 at 7 p.m. ETWhere: KeyBank Center in Buffalo, New YorkTV: ESPN+Live Boxscore: FOX Sports Sabres vs Blackhawks Betting Information Favorite Puck Line Favorite Puck Line Odds Underdog Puck Line Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline Sabres -1.5 136 -162 6.5 105 -125 -180 +150

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Sabres vs. Blackhawks Prediction

ATS Pick: Blackhawks (+ 1.5)
O/U Pick: Under (6.5)
Score Prediction: -Blackhawks 4 – Sabres 3

Sabres vs. Blackhawks Betting InsightsIn 11 games this season, Buffalo and its opponent have combined for more than 6.5 goals.Chicago has combined with its opponent to score over 6.5 goals in seven of 20 games this season.The two teams combine to score 6.2 goals per game, 0.3 fewer than this game’s total.These teams together concede 6.1 goals per game, 0.4 fewer than this game’souting’s total.In terms of goals scored, the Sabres are 25th in the league, and the Blackhawks are 10th.The Blackhawks are third in the league in goals allowed, and the Sabres are 26th.Sabres StatsThe Sabres’ 57 total goals (2.8 per game) make them the 25th-ranked scoring team in the NHL.Buffalo ranks 26th in goals against, allowing 71 total goals (3.6 per game) in league play.Their -14 goal differential ranks 28th in the league.The 10 power-play goals Buffalo has put up this season rank 21st in the NHL (on 61 chances).The Sabres’ 16.39% power-play conversion rate ranks 23rd in the league.The three shorthanded goals Buffalo has scored this season rank third among all NHL squads.Sabres LeadersBlackhawks StatsThe Blackhawks are 10th in the NHL in scoring (66 goals, 3.3 per game).Chicago concedes 2.6 goals per game (51 total), the third-fewest in the league.They have the second-best goal differential in the league at +15.With 14 power-play goals (on 58 chances), Chicago ranks 12th in the NHL.The Blackhawks score on 24.14% of their power plays, No. 9 in the league.In terms of shorthanded goal, Chicago has one.Blackhawks Leaders

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