The Buffalo Sabres and Chicago Blackhawks hit the ice in NHL play at KeyBank Center on Friday, Nov. 21 at 7 p.m. ET. The matchup airs on ESPN+.

Buffalo’s most recent game was a 6-2 home loss against the Calgary Flames on Nov. 19.

Chicago’s last game was a home loss, 3-2, against the Seattle Kraken on Nov. 20.

Before this matchup, here’s everything you need to get ready for Friday’s action.

Watch Sabres vs. Blackhawks on Fubo! (Regional restrictions may apply)

Buffalo Sabres vs. Chicago Blackhawks odds and betting lines

NHL odds courtesy of BetMGM Sportsbook. Odds updated Friday at 1:51 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Sabres (-189)Underdog: Blackhawks (+156)Over/under: 6Sabres vs. Blackhawks game info and start timeDate: Friday, November 21, 2025Time: 7 p.m. ETTV channel: ESPN+Live stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on ESPN+

Watch Sabres vs. Blackhawks on Fubo! (Regional restrictions may apply)

Sabres stats and trendsBuffalo has been victorious twice in six games as the moneyline favorite this season.The Sabres have not had moneyline odds lower than -189 in a game this season.Buffalo has a 65.4% chance of winning this game, looking at the moneyline odds.Buffalo and its opponent have gone over the current 6-goal total in 14 of 20 matches (70.0%) so far this season.In the last 10 games, the Sabres have gone 3-5-2 (55.0% of possible points).They are scoring at a 2.7 goals-per-game average (27 total) during that stretch.On the defensive side, the Sabres have given up 3.5 goals per game (35 total) over those 10 matchups.Blackhawks stats and trendsThe Blackhawks have been made the underdog 19 times this season, and upset their opponent 10 times.Chicago has a record of 2-3 in games when bookmakers list the team at +156 or longer on the moneyline.The win probability for the Blackhawks, implied from the moneyline, is 39.1%.Chicago’s games have gone over 6 goals in eight of 20 chances this season.In their last 10 matchups, the Blackhawks are 5-3-2 to earn 65.0% of the possible points.They are scoring at a 3.3 goals-per-game average (33 total) over that time.On the defensive side, the Blackhawks have given up 2.6 goals per game (26 total) in those 10 matchups.