Two teams near the bottom of the Eastern Conference standings square off when the ninth-place Pittsburgh Penguins (10-6-5) host the 15th-place Buffalo Sabres (9-9-4) at PPG Paints Arena on Wednesday at 7 p.m. ET.

Pittsburgh’s last game was a 3-2 overtime home loss to the Seattle Kraken on Nov. 22.

Buffalo won at home in its most recent game on Nov. 23, 4-1 over the Carolina Hurricanes.

Here is everything you need to get ready for Wednesday’s action.

Watch Penguins vs. Sabres on Fubo! (Regional restrictions may apply)

Pittsburgh Penguins vs. Buffalo Sabres odds and betting lines

NHL odds courtesy of BetMGM Sportsbook. Odds updated Tuesday at 5:51 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Penguins (-120)Underdog: Sabres (+100)Over/under: 6.5Penguins vs. Sabres game info and start timeDate: Wednesday, November 26, 2025Time: 7 p.m. ETTV channel: ESPN+Live stream: Watch on Fubo (Regional restrictions may apply)Live stream: Watch on ESPN+

Watch Penguins vs. Sabres on Fubo! (Regional restrictions may apply)

Penguins stats and trendsPittsburgh has won two of its six games as a favorite this season.The Penguins have been victorious twice through six games with moneyline odds lower than -120 this season.Pittsburgh has a 54.5% chance of winning this game, according to the moneyline odds.Pittsburgh and its opponent have gone over the current 6.5-goal total in nine of 21 games this season.In the last 10 games, the Penguins have secured 50.0% of the possible points with a 3-4-3 record.They have scored 24 goals during that span.Defensively, the Penguins have given up 26 goals (2.6 per game) in those 10 matchups.Sabres stats and trendsThis season the Sabres have six wins in the 15 games in which they’ve been an underdog.Buffalo has won five of its 12 games when it is the underdog by +100 or longer on the moneyline.The moneyline implies a 50.0% chance to win for the Sabres.So far this season, 54.5% of Buffalo’s games (12/22) have had more goals than Wednesday’s over/under of 6.5.In the past 10 games, the Sabres have earned 65.0% of the possible points with a 4-5-1 record.They are scoring at a 3.4 goals-per-game average (34 total) during that span.Over on the defensive side, the Sabres have allowed 32 goals (3.2 per game) in those 10 matchups.