Welcome back to NHL Predictions. Each day, our writers here at Last Word On Hockey look at the games and give in-depth analysis. Our team breaks down the key matchups, storylines, and stats, then makes predictions based on how they might play out. Our featured game of this edition is the Buffalo Sabres taking on the Florida Panthers. Don’t forget to check out more NHL Predictions, as our writers continue this series throughout the 2025-26 season.
NHL Predictions
Buffalo Sabres vs Florida Panthers
Head-to-Head: Sabres 2-1 Panthers
How to Watch: US TV: Scripps Florida; MSG Buffalo; ESPN+. Canada TV: Sportsnet.
Time: 7 p.m. Eastern Standard Time (EST)
We open up NHL predictions with our featured game between the Buffalo Sabres and the Florida Panthers. Buffalo is slated give former Florida goalie Alex Lyon the start in this game. However, always check social media before locking in a daily fantasy starter. The Sabres are 7-2-1 in their previous 10 games, including a victory over the New Jersey Devils last time out. Gold medalist Tage Thompson leads the club in goals (31) and points (61) so far this season.
Florida is coming off a victory over the rival Toronto Maple Leafs in its first game back from the Olympic break. However, the Panthers are 5-5 in their last 10 games entering this matchup. Daniil Tarasov is the likely starter after Sergei Bobrovsky got the call versus the Leafs. Sam Reinhart is first on the team in assists (29) and points (56) for the Panthers.
Both teams are trying to get points for different reasons. However, the Sabres should collect the win.
Prediction: Sabres win 4-2.